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Metagenome Program
… The Metagenome Program uses advanced sequencing technologies to decode the genomes of microbes in their natural environments. This work encompasses bacteria, archaea, and … to assess microbial activity across ecosystems.  By studying microbial communities and their interactions, the …
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Single Cell Research Group
… Research in the Woyke laboratory focuses on the utility of … access genetic material of uncultivated taxa of interest. One such effort is targeted at environmental cells that are … widening since 2005. This gap is also reflected in the strongly biased representation of sequenced genomes in the …
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Environmental Genomics Group
… Research in the Eloe-Fadrosh group focuses on using genome-resolved … computational approaches to sift through thousands of metagenomes for signatures of viruses and novel microbial … Our research focuses on the assembly of metagenomic sequence data into microbial …
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JGI@25: Cow Rumen and the Early Days of Metagenomics
… In honor of the JGI's 25th anniversary in 2022, we have … and environmental challenges. Oh, the magical world of the cow stomach. Rumen – and its microbes – are really a … fuels from plants is the high cost and resource requirements of processing these sturdy materials, rumen …
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Natural Prodcast Episode 12: Nadine Ziemert
… about natural products and the science and scientists of secondary metabolism. Welcome back. This will be episode 12 of … or the genes that you are analyzing. And then we’re building phylogenies a lot, making phylogenetic trees, and … that easily can identify secondary metabolite pathways in metagenomes, which is still hard to do. We are mining a lot …
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Sequencing Technologies & Products
…   Our Sequencing Technologies Group is well-integrated across JGI … which includes the Sequencing Technologies team, relies on collaborations with Science Programs and Operations teams … (quality assurance/quality control [QA/QC]), large-scale liquid handling automation, and sequence analysis. …
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How to Submit Sequencing Samples
… Below is a brief description of the process needed to prepare and ship samples for sequencing by the JGI.  Additionally it includes instructions on accessing sample-level … 1) Review JGI sample QC requirements and protocols Obtaining DNA and RNA of suitable … at the JGI. The quality of the starting material is one of the greatest predictors of a successful sequencing …
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Natural Prodcast Episode 10: A Primer on Genome Mining
… about natural products and the science and scientists of secondary metabolism. Welcome back for our second season of … the pieces that attached to the other pieces, and sort of building out the puzzle from there to find that vein of gold. … and archaeal genomes that were created – these are Metagenome Associated Genomes, or MAGs. So these are genomes …
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New Lineages of Life Group
… Our research is focused on the discovery and characterization of novel bacterial, archaeal and eukaryotic microbes and viruses in environmental sequence data. We use multi-omics … challenge our understanding of viral complexity and evolution Our research focuses on discovering and characterizing …
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JGIota: Looking Back at How Cow Rumen Samples Landed on a Syllabus
… Back in 2011, JGI-supported researchers published a paper in the … to identify over 27,000 microbial genes. The data from that study is now used across California State University campuses for biotechnology education as part of a course-based undergraduate resource …
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Natural Prodcast Episode 2: The Primer, Part 2
… Prodcast,” a podcast about the science and scientists of secondary metabolism.  DAN: Hi, again. This is Dan, and you’re … metabolites. And they often use primary metabolites as building blocks to produce novel molecules. And so we’ve got … them as very small fungi. And this came from a growth on a cow’s cheek. Historically, before antibiotics were common, …
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Metagenomic Discovery of Biomass-Degrading Genes and Genomes from Cow Rumen
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