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Sequencing Technologies
The Sequencing Technologies Group applies cutting edge molecular capabilities and state-of-the-art next-generation sequencing to enable biological discovery by the JGI and …
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Single Cell Research Group
Research in the Woyke laboratory focuses on the utility of single-cell methods to access genetic material of uncultivated taxa … to only three phyla. The Woyke group uses single-cell sequencing as a means to begin filling this gap. A primary …
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Micro-Scale Applications Group
… technology in order to enhance the quality of single-cell genomes and directly link functional information with … that allow us to select specific uncultivated microbes for sequencing based on their level of metabolic activity …
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Metabolomics Technology Group
Our lab is using mass spectrometry based metabolite profiling to provide direct biochemical datasets to improve our understanding of microbial metabolism. Of particular interest is …
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Offerings & Capabilities
… science by generating data in three overarching categories: Sequencing, Synthesis and Metabolomics. Strong internal … automation, and further advancing sequence applications, single cell genomics, DNA synthesis, and metabolomics.   … Deputy …
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Microbial Program
The JGI’s Microbial Program focuses on using cutting-edge sequencing, annotation and analysis techniques to explore … of bacteria and archaea in their natural environments using single cell approaches. This includes linking strain-level genetic …
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Products
The JGI has diverse capabilities in: DNA and RNA sequencing, Sample and library preparation, DNA synthesis … percentile*) DNA Synthesis Constructs <5kb in size Single gene or multiple small genes assembled to less than … Assembly, annotation ( IMG/M ), mapping 273/273 Metagenome Cell Enrichments Obtained by physical separation of a …
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FICUS
The Facilities Integrating Collaborations for User Science (FICUS) call … to DOE mission is appropriate. For accepted proposals, sequencing, synthesis, metabolomics and analysis will be … Accessing Resources at Multiple DOE User Facilities with a Single Proposal describes the resources available from the …
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Natural Prodcast Episode 7: Ben Shen
… started collaborating with Ben and his group to work on sequencing, synthesis and genome mining technology to help … is always associated with toxicity, basically, killing cells. ALISON: Right, because they’re so reactive. BEN: … DAN: Yeah, I don’t think your lab is gonna tackle that single handedly, right? So, yeah, getting the community …
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Natural Prodcast Episode 14: Nigel Mouncey
… a great opportunity to learn more about JGI, hear some excellent talk from our users and from other invited guests, … NIGEL MOUNCEY: Oh, sure. I think our legacy obviously is in sequencing.  DAN: Of course.  NIGEL MOUNCEY: Sequencing the … and the stabilized isotope probing work that we’re doing, single cell work we’re doing. And using these together along …
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Natural Prodcast Episode 10: A Primer on Genome Mining
DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast, a podcast about natural … really the same kind of thing. Before the age of genome sequencing, we had to basically break up the pieces of DNA …
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Microbiome Data Science Team
… other omics technologies.  The exponential growth of DNA sequencing data, coupled with recent computational … types) (Nature Communications 2017, Science 2018, Molecular Cell 2019) and massive reconstruction of genomes from … Bowers RM, et al. (2017) Minimum information about a single amplified genome (MISAG) and a metagenome-assembled …
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