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… bucket. [LAUGHS] I don’t know that that’s ever necessarily like a good description of anyone because chemistry means a … does some really exciting work there. And I thought, well, why don’t we try to go to Alaska and see what we can find … with any kind of gene cluster identification, doing it with sequence alone you have to have some kind of a template to …

When submitting sequences to the JGI DNA Synthesis program, please include the following items: … Sequence files for all constructs should be emailed to  …

… least, talk to us, first about my definitions of things and why I am wrong, and also talk about some of the great … it’s not central because it’s not just supports energy and yeast-type function, it’s very specialized function, which … to approach it is more related to what JGI does, which is sequence genomes. And we just published last year in the …

… out introns and dealing with, you know, weirdness in the sequence. You know, some clusters are not clustered…   … it so easily with fungi. So…   NANCY: Yeah, I don’t know why. For example, with that – actually there’s a good talk … the fungi vary in number of chromosomes. Like, ironically, yeast, which has a small genome has 15 chromosomes. Where …

The Sequencing Technologies Group applies cutting edge molecular capabilities and state-of-the-art next-generation sequencing …

… some fun interviews, unless you want to fact check us. I like fact-checking, so go nuts. But here, in this first … stories about natural products, so you can get a feel for why I think they’re so important, and we’ll start to explain … susceptible to a fungal infection of rye grain – a specific fungus, Claviceps purpurea, can infect grain. And when it …

… the metagenomics and gut microbiome, as I think that it’s like a perfect storm in terms of fundamental knowledge and … the paradigm of how to discover natural products. So, why I’m very excited to be working with Dan, you, with the … develop enabling technologies. ie how to translate the ATGC sequence into discrete small molecules. So, Dan, I’m very …

… having me. DAN: We know each other pretty well. So I feel like it’s always fun to talk to you. I’m particularly … at genomes and seeing where the really hard things to sequence were, and wondering what those … what those were … functional was these secondary metabolite pathways. So why was that? What is it about secondary metabolite pathways …

… more than 50,000 genomes that we derived from meta-genome sequences. As always, you’ll find transcripts and show notes … for genetic elements of interest, you know, something like treasure. DAN UDWARY: There you go. ALISON TAKEMURA: It … for us– what organisms people use for genome mining, why it’s called genome mining, how the biosynthetic gene …

… that are known to be sources of secondary metabolites, like sponges were a really common source for people to try … DAN: Alright, so I think we’ve covered a little bit about why they’re important. But one of the things I did want to … live in the root nodules of plants. And these guys were sequenced, and you can see that different Frankia have …

The Joint Genome Institute's DNA Synthesis Platform capabilities support researchers exploring how to convert sequence into functional assessments. This is done by … tools to automate sequence design for assembly by Gibson, Yeast recombination and Golden Gate methods … gRNA-SeqRET … …

Software engineers in the Synthetic Biology Informatics Group … tool BOOST , which provides a suite of tools to automate sequence design for assembly by Gibson, Yeast recombination and Golden Gate methods SynTrack and …