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DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s … producing molecules that are helpful to the plants. And so, understanding those broader environmental and ecological … to get involved in secondary metabolism more or even just starting to get involved, what might you recommend? DAN …

… look at the soil microbes present a year after a wildfire. The Science After a wildfire burns, recovery begins at the forest floor. Within the soil, a … extreme wildfires, more and more forests are under threat. Understanding which microbes in the soil persist after a …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … has recognized how important natural products are to understanding the natural environment, and so our Director, … is a chemical compound called geosmin that’s produced by soil bacteria that live all over the place. So that smell of …

Program works to uncover the roles of small molecules in biological systems, linking them with genomic data to enhance our understanding of genome science, organisms, and ecosystems … the program supports foundational research related to soil nutrient cycling and health, terrestrial biogeochemical …

… right. Welcome back to Natural Prodcast. I did it. I’m keeping to my schedule. This should be coming out on the first … a lot of people hedge their way into natural products by starting out in synthesis and then discovering more-- … can do these small rings, and so I think we need a better understanding of that. We have a crystal structure, and …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … as you see, the number of new natural product molecules was starting to decline around the 70s. It’s really very, very … in terms of – well it’s really simple in terms of understanding it because it’s an assembly line. You just go …

… … DAN: You’re listening to the US. .Department of Energy Joint Genome … for antibiotics and the microbes that make them is in the soil. There’s … uh… there’s an issue there though, in that … for many millions, sometimes billions, of years. And understanding how those changes that evolution brokers are …

… the process needed to prepare and ship samples for sequencing by the JGI.  Additionally it includes instructions on … step for many projects at the JGI. The quality of the starting material is one of the greatest predictors of a … Protocol JGI’s Small RNA Sample QC Protocol DNA Extraction 101 : tips, kits, and protocols (from PacBio) Guidance for …

… starts with a User Agreement — before any work can begin, including the submission of samples for sequencing, or the … director or supervisor for the appropriate contact name, email address and phone number for the signing official. …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … of secondary metabolism in the environment, and, sort of, understanding – like we’ve talked about – how bacteria or … products because they’re easy to find. They grow in the soil. These are the same guys that produce geosmin. And so …

… … DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s … actually can learn just by really digging into the data and understanding what’s going on there. And now, that’s all I … of these environments? NADINE ZIEMERT: So we started with soil. But we also have, in collaboration with other people, …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … a master plan. And Tucson was a magical place for me as a starting faculty member. To start a lab. You know, all of my … in a laboratory. And so, for us, we’re fascinated by understanding the logic of nature and how it can control …