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… of secondary metabolism. Welcome back. This will be episode 12 of Natural Prodcast. And it’s our conversation with … Europe. So if there are any kind of dated references to the news, that’s why. But it was a really fun conversation. And … this? NADINE ZIEMERT: It wasn’t that long ago, but maybe 2006, 2007, or something like that. And we actually found the …

… and materials. The proposal submission deadline is March 31, 2026 .  … (CMMs). Click for a list of CMMs and the results of the 2023 DOE Critical Materials Assessment . While we expect most … the Molecular Foundry, the project needs to be scoped for 12 months or less. We can help you scope that part of the …

… in this hypersaline environment, which can range from 8% to 28% salinity. We have toxic metals, so these concentrations … there a way to do that? DAN UDWARY: Well, so there’s good news and bad news on that. So one of the things that we’re … happening. And so we should have somewhere around 10, 11, 12 million BGCs in the database on the release, and that’s …

… as well as a unique opportunity to complete a California K-12 science or math teaching credential as an undergraduate …

… right? BEN: Yeah, yeah. Well, we are at [10 to the] minus 12 [Molar concentration]- is sufficient to kill cells. So … So I wanted to ask you also about – because you were in the news recently – TSRI has acquired the Pfizer strain … genome, the genome predicts they often can produce around 30 – more than 30 compounds. So, this was a complete …

… in Yu et al, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2004, 1253–1262, 70:3 ALISON TAKEMURA: And so did you succeed in … Microbiomes” paper is here . Read the associated JGI news release here . Software we discussed, used for genome …

… eukaryotes in the open ocean .”  Current Biology , Volume 34 Issue 22. Krinos, A.I., Mars Brisbin, M., Hu, S.K. et al. … conclusions .”  Nature Communications Volume 15 Article 9873. Buscaglia, M. et all (2024) “ Adaptation strategies of …

… proposal submission. Sequence requests should not exceed 3 Tb in total. Proposals for this call may be submitted at …

… from metagenomes. mSystems 9:e00888-24. https://doi.org/10.1128/msystems.00888-24 Coclet, C., Sorensen, P.O., Karaoz, U. … across Earth’s biomes. Nature Microbiology. 4, 1895–1906. https://doi.org/10.1038/s41564-019-0510-x Roux, S. et …

…   700.0     8,760     Q1 2026 175 313.081 179% 2,208 2,064 95.4% Q2 2026 175 243.806 139% 2,160 2,112 99.8% Q3 2026 175     2,164     Q4 2026 175     2,208     … 175 309.533 177% 2,140 2,184 102.1% Q4 2025 175 492.249 281% 2,164 2,208 102.0% *Includes Illumina and PacBio …

… like a nice summer day in Seattle I think this was like 2013 or 2014. And antiSMASH — I know you’ve interviewed Marnix … access to the whole sigma catalog of precursors in their 12C form. You can feed those and look for incorporation in … would grow up our bacteria on 13C methane or methanol, feed 12C methionine, and we were able to pull out the quorum …

… 10 to the negative 9th. Picomolar, 10 to the negative 12th. DAN: Yeah. So very-- BETSY PARKINSON: Very, very-- … thioesterases, we were actually able to find approximately 300 with NRPSs nearby. And of those once we did the … the issues is in order to make the tetrapeptide, that's a 12 membered ring. And there's extreme ring strain in 12 …