Search

… DAN: Hello, everyone, and Welcome back for Episode 14 of Natural Prodcast . There’s been a lot going on, so I … never forced it on me, but we always had these scientific news magazines lying around at home. And I would just pick … sequencing and genome mining with using DNA synthesis to express clusters metabolomics to be able to actually identify …

… welcome back to Natural Prodcast, and this will be episode 11. This continues our little sprint on genome mining. In … was a proposal on synthetic biology of engineering gene expression in bacteria – however, the professor was actually … they had actually devised a standard called the “ Minimum Information of Any Sequence” (MIxS) standard a number of …

… as metagenomics and metatranscriptomics provide invaluable information on virus diversity and activity in microbial … from metagenomes. mSystems 9:e00888-24. https://doi.org/10.1128/msystems.00888-24 Coclet, C., Sorensen, P.O., Karaoz, … of hypermutation in the global microbiome. Nat Commun 12, 3076. https://doi.org/10.1038/s41467-021-23402-7 Roux, S. and …

… metagenomic approaches to identify and characterize genomic information from uncultivated microbes and viruses. We … microbiomes. mSystems0:e01744-24. https://doi.org/10.1128/msystems.01744-24 Oliver, T., Varghese, N., Roux, S. et … 39 , 499–509 (2021). https://doi.org/10.1038/s41587-020-0718-6 I-Min A Chen, Ken Chu, Krishnaveni Palaniappan, Anna …

… offering new approaches to address some of the world’s most pressing challenges. … GOLD is a web resource for comprehensive access to information regarding genome and metagenome sequencing …

… there a way to do that? DAN UDWARY: Well, so there’s good news and bad news on that. So one of the things that we’re … or I tried this knock-on. I tried these promoters to express this natural product cluster. It just didn’t work. And … happening. And so we should have somewhere around 10, 11, 12 million BGCs in the database on the release, and …

… global diversity of alternative genetic codes (Science 2014), unearthing hundreds of thousands of new viral genomes … the human gut microbiome. Nature Biotechnol.  39(1):105-114. Schulz F, et al. (2020) Giant virus diversity and host … of metagenomics software. Nature Methods  14(11):1063-1071 Bowers RM, et al. (2017) Minimum information about a …

… modules Currently 206 genomes have been selected with 11 published manuscripts published to-date Testimonials: … Resour Announc 0:e00891-25. https://doi.org/10.1128/mra.00891-25 . B. Christenson, I. Nouioui, C. Daum, M. … DSM 14810 (JK 615T) and Butyrivibrio fibrisolvens DSM 3071 (D1T). Microbiol Resour Announc. 2024 0:e00517-24. …

… convention went– since the protocol went into force in 2014. There’s now a website that has a lot of resources that … then my lab pleaded mercy, and I said, OK, we’ll just do 2011 to present day. And it was still like 4,000 articles we … plants and bringing them back is not your jam, the good news is there’s this amazing resource that can be provided …

… trying to understand the enzymology. So we would actually express the genes and do the biochemistry to understand what … this is Challis et al, Chemistry and Biology, 2000, 211-224, 7:3 And so, you can then make predictions about … Nature  Biotechnology . 2020 Nov 9. doi: 10.1038/s41587-020-0718-6) DAN UDWARY: Yeah, I think that might be a good …

… enabled to log in. Check our Help Site for additional information, including a Login Walkthrough and FAQ . … GOLD is a web resource for comprehensive access to information regarding genome and metagenome sequencing … potential, antibiotic resistance genes, and ecosystem information. …

… like a million more questions for him, but we were a little pressed for time on this interview, so I’m hoping we can … National Lab. You can find links to transcripts, more information on this episode, and our other episodes at … came together to define a common language and share information to kick-start this newer area of secondary …