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… getting them out to you all. But for now, here is episode 10 of Natural Prodcast, the primer on genome mining. Hey, … Microbiomes” paper is here . Read the associated JGI news release here . Software we discussed, used for genome … reviews of genome mining: Ziemert, Alanjary, and Weber’s 2016 overview of genome mining (open access) The Challis/Corre …

… so there are– I hesitate to make a guess but maybe 50 to 100 different strains and they are in individual tubules.  … in the field, these glacial bacteria grow slow and it’s not 100% clear that we know what their biological activities … call this the needle in the Haystack. Because if we have 10,000 features which one do we look at because we are a …

… available at Google Scholar. Schulz, C Abergel, T Woyke (2022) Giant virus biology and diversity in the era of … components. Science, 356 (6333), 82-85 Schulz et al. (2016) A Rickettsiales symbiont of amoebae with ancient … in the Gammaproteobacteria. Scientific reports. 5 (1), 1-10 Schulz et al. (2014) Life in an unusual intracellular …

… from candidate phyla, major branches in the phylogenetic tree without cultivated representatives. The “Great … through global metagenomics.” Nature 578(7795): 432-436 (2020). Seshadri R., Leahy S. C., Attwood G. T., Teh K. H., … and sequencing of rumen microbiome members from the Hungate1000 Collection.” Nat Biotechnol 36(4): 359-367 (2018). …

So they’re in the picomolar range. ALISON: Picomole… is [10 to the] minus twelve, right? BEN: Yeah, yeah. Well, we … So I wanted to ask you also about – because you were in the news recently – TSRI has acquired the Pfizer strain … we have here – all of them were collected before 2016, before that true enforcement of the Nagoya protocol. And …

Europe. So if there are any kind of dated references to the news, that’s why. But it was a really fun conversation. And … in the early 2000s? Late 2000s? NADINE ZIEMERT: No, yeah, 2010. ALISON TAKEMURA: 2010, OK. You’re a young faculty. … all these very, very related genomes, right – on their 16S level, they’re almost identical! But seeing all these …

… hard to believe in retrospect. BILL FENICAL: Well, in 2021, absolutely hard to believe. But when you go way back, … convince those people of that fact, however, a long time, 10 years! ALISON TAKEMURA: Wow. It’s all happened so fast. I … course using modern phylogenetic tools measuring genes, the 16S gene, and comparing it with everything that’s known. So …

… heard of the Salem Witch Trials back in the what? 15th, 16th century.  ALISON: Yeah, I lived in Massachusetts for a … But where taxol comes from is, from the bark of the yew tree, is where it was originally discovered. And so that … right? It turns out, it takes the bark from three yew trees in order to make enough or to isolate enough taxol to …

Xenorhabdus cabanillasii DSM17905, Xenorhabdus ehlersii DSM16337, Xenorhabdus japonica DSM16522 R Robertson, et. al.  2023 . Microbiology Resource Announcements. 2023 12 (10), e00548-23 Whole genome sequence of the denitrifying …

Myco-Ed has:  ~50 lineages selected for sequencing 16 genomes released 20 members from 15 institutions 300+ …

… we talked about sponges, go pull a sponge or extract some tree bark. And so you’re just taking something, you’re … the number was. But I want to say it was like less than 10. Since, you know, a recent decade.  DAN: I’m sure that’s … to check her stat and she was absolutely correct. Since 2010 there have been eight new antibiotics added to the …