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IMG Group
The IMG group owns and maintains integral components of JGI’s … and exa- scales on multicore and many core architectures with the ultimate objective of facilitating omics-based … (Alignment fraction, AF) have been computed for nearly 28,000 bacterial and archaeal genomes. By clustering genomes …
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Natural Prodcast Episode 10: A Primer on Genome Mining
… found in Yu et al, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2004, 1253–1262, 70:3 ALISON TAKEMURA: And so did you … of Biosynthetic Clusters , which is a subsection of the IMG data portal , which is a larger portal for microbial … of Earth’s Microbiomes. Nature  Biotechnology . 2020 Nov 9. doi: 10.1038/s41587-020-0718-6) The GEM catalog expands …
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Natural Prodcast Episode 11: Marnix Medema
MIBiG, and newer efforts, like BiG-scape and BiG-SLiCE, and now the BiG-FAM database of biosynthetic gene cluster … to tell a quick story. Looking back, the year was probably 2010, 2011, I was a, uh- actually, I’ve got the t-shirt on … of biosynthetic gene clusters. But with all of the other IMG kind of hooks into IMG’s data. IMG being Integrated …
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Partnerships: Adopt-A-Genome
Adopt-a-Genome has:  11 CSU educators working with the JGI 120 genomes claimed (or about one per student) Seven … biological insights from sequence data, employing IMG data and tools for comparative analysis, visualization … entomopathogenic nematodes: Xenorhabdus cabanillasii DSM17905, Xenorhabdus ehlersii DSM16337, Xenorhabdus japonica …
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Natural Prodcast Episode 19: Bill Fenical
… metabolism of some more novel marine bacteria. You know, I first met Bill as a postdoc working under Brad Moore … that there was almost nothing. Now, this is back in the 1970s. So, I thought to myself, maybe I can use my background … seems hard to believe in retrospect. BILL FENICAL: Well, in 2021, absolutely hard to believe. But when you go way back, …
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Natural Prodcast Episode 24: Jackie Winter and SMC
My new co-host, Jackie Winter, has been on a few episodes now, and I figured we were way overdue to give her a proper … in this hypersaline environment, which can range from 8% to 28% salinity. We have toxic metals, so these concentrations … to help our users. So for those who are familiar with JGI’s IMG data portal , the Integrated Microbial Genomics, there …
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Natural Prodcast Episode 17: Cassandra Quave
… plants for drug discovery in antibiotics, anticancer, and now COVID. We also wanted to talk to her because she’s … the convention went– since the protocol went into force in 2014. There’s now a website that has a lot of resources that … wasn’t an MRSA strain at the time because that was in the 1980s. I’m showing my age now. So early 1980s we didn’t have– …
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Metagenome Program
… encompasses bacteria, archaea, and micro-eukaryoes, along with their associated viruses and mobile genetic elements. … Sequencing technologies have expanded viral diversity knowledge, enabling global exploration. We develop … computational tools for analyzing viral fragments via IMG/VR and methods to capture  environmental viral …
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Natural Prodcast Episode 20: Brian Bachmann
… went on to work at a groundbreaking company in the early 2000s called Ecopia, which was a very early genome mining … pathways was hard and expensive to do. As I said, Brian is now at Vanderbilt, and he’s doing some amazing research in … https://sim.confex.com/sim/np2023/meetingapp.cgi/Paper/46926 Jen Wurm:  …
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Natural Prodcast Episode 1: The Primer, Part 1
… metabolism – field, though, is real, and it’s a field with very real and truly amazing science with a long … it’s probably going to help you some to have some basic knowledge of modern biology. We’re trying to keep this as … I have been in – working in secondary metabolism for almost 20 years now. Which when I did the math, that was a surprise …
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Natural Prodcast Episode 7: Ben Shen
Episode 7 of the Natural Prodcast. It’s been about a month now since we dropped our first six episodes, and now after … because they’re so reactive. BEN: …going back to the 1950s. But the structure of which was not known until the … right? BEN: Yeah, yeah. Well, we are at [10 to the] minus 12 [Molar concentration]- is sufficient to kill cells. So …
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Natural Prodcast Episode 12: Nadine Ziemert
… secondary metabolism. Welcome back. This will be episode 12 of Natural Prodcast. And it’s our conversation with Nadine … you can always find at naturalprodcast.com . You should know we’ve recorded this a few months ago when we were at the … in the past, we’ve had these monolithic databases, NCBI and IMG , that have a lot of data and really useful data, really …
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