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All participants and staff of the JGI events are required to adhere to the following Code of Conduct. Event organizers will enforce this Code throughout the entire event. All participants are …

Guiding Principles All staff members of the US Department of Energy (DOE) Joint Genome Institute (JGI) commit to … In working toward a shared vision with members of the JGI advisory committees, we welcome and encourage …

The JGI’s DNA Synthesis Program supports a wide range of projects, from single-gene synthesis to the synthesis of … the program enables the design and synthesis of complex genetic pathways and biosystems. It The program fosters … and efforts to refactor entire chromosomes, such as a yeast chromosome project. These advancements contribute to …

Research in the Woyke laboratory focuses on the utility of single-cell methods to access genetic material of uncultivated taxa of interest. One such … M., Visel A., Woyke T ., Kyrpides N.C. & Rubin E.M. Stop codon reassignments in the wild. Science 344, 909-13 (2014). …

The focus of this group, in recent years, has been to bring generalizable technologies to bacteria, yeasts and algae previously with little to no genetic tools enabling heterologous expression and …

ActDES, which is a curated database of actinobacteria for evolutionary studies, and hopefully we can catch him again … example, in terms of the stereochemistry, such that single changes can lead to a particular high activity towards a … So we had a series of criteria to say this is a bunch of genetic material that exists in one copy, and it is …

ALISON TAKEMURA: I know that it’s looking in the genome for genetic elements of interest, you know, something like … isn’t itself medicine, but the coding within the DNA codes for proteins that do the chemistry that put molecules … ALISON TAKEMURA: Hmm. Well, I think, I mean from an evolutionary perspective, I would think that genes that are …

… and other omics technologies.  The exponential growth of DNA sequencing data, coupled with recent computational … include exploration of the global diversity of alternative genetic codes (Science 2014), unearthing hundreds of thousands of …

… … Dan Udwary: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast, a … of these crazy genes, some of these enormous genes that encode these very large enzymes. And I was like, OK, wow, … especially across species that might be a little bit more genetically distant where the BGCs may have drifted but they …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … looking at that I’m a very visual person. So, when we make genetic mutants in a fungal isolate, I can see something … the fungi vary in number of chromosomes. Like, ironically, yeast, which has a small genome has 15 chromosomes. Where …

… automations for DNA design, assembly and analysis Overview of synthesis products The JGI DNA Synthesis platform enables … CRISPR gRNA design tool  … BOOST provides a suite of tools to automate sequence design for assembly by Gibson, Yeast recombination and Golden Gate methods … gRNA-SeqRET … …