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Fungal & Algal Program
The Fungal & Algal Program explores the vast diversity of fungi and algae to unlock their potential for bioenergy, … program investigates the biological mechanisms that enable fungi and algae to play a vital role in carbon cycling, … on large-scale sequencing efforts that survey the vast phylogenetic and ecological diversity of fungi and algae, …
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Natural Prodcast Episode 11: Marnix Medema
Master’s student at the University of Groningen and then I wrote my own grant proposal in the hope that it would get … Marnix Medema: Yeah, exactly. There is no black and white in clustering in general in computer science. Dan … metabolomics, and natural products in plants, fungi, and microorganisms. If you want to collaborate, let …
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Secondary Metabolites Program
… the exploration of secondary metabolites across bacteria, fungi, algae and plants. These molecules, which are not … communication. Studying how these compounds are biosynthesized and their roles in the environment, can unlock new … conditions, with only a small portion of the biosynthetic gene clusters (BGCs) being expressed. The program works to …
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Plant Program
… to regulate Earth's carbon balance, to exploring the genetic basis of how plants have naturally adapted to varied … including deep learning algorithms for gene annotation and protein folding models, to improve the accuracy of functional … … Phytozome is the JGI's Plant Comparative Genomics portal. Families of related genes representing the modern …
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Natural Prodcast Episode 13: Francisco Barona Goméz
… be the amino acid that is relevant for the synthesis of proteins, and will more often end up in the active site of an … are microbes that will actually redefine how you synthesize nucleotides. Stuff that are at the core of what we call … metabolomics, and natural products in plants, fungi, and microorganisms. If you want to collaborate, let …
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Metabolomics Program
… metabolomics fuels the discovery  of novel metabolites, genes, and proteins. It also enables exploration of energy and nutrient … biological and environmental samples — including microbes, fungi, plants and soils. Through a combination of …
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Natural Prodcast Episode 16: Marcy Balunas
… just deposit and take off. And so they must be chemically protected in some way and lo and behold it’s this bacteria. … working on that aspect and it’s quite active against some fungi. But we’re also really interested in distribution. So … there’s no reason for that diversity of thought to be all white males for sure. And I think natural products does a …
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Natural Prodcast Episode 24: Jackie Winter and SMC
… with Christian, I started getting a little bit more into fungi and learning the differences of all the genetic … types of particulate like 2.5, 10 PPMs and just the size of the particle and how far they can actually travel. … are not publicly available because sometimes we want to protect the clusters we’re working on and not get scooped. …
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Natural Prodcast Episode 2: The Primer, Part 2
… bacterial sacred metabolite, and ergot alkaloids come from fungi, and Taxol from plants. Plants, fungi, bacteria, … They might have enough nutrients, but they might want to protect those nutrients with antibiotics. They might need to … like a bunch of colonies on a petri dish. It’s a black and white photo. It almost looks like the moon, because you have …
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Natural Prodcast Episode 10: A Primer on Genome Mining
… itself medicine, but the coding within the DNA codes for proteins that do the chemistry that put molecules together … in the earlier primers. In bacteria, at least, and in most fungi, biosynthetic gene clusters, which are the genes that … cluster makes a product and how a product should be synthesized based on its structure, that we should be able to tie …
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Natural Prodcast Episode 5: Brad Moore
… them that it looked to be of a certain number of modules in size, they then quickly were able to then solve the … on marine actinobacteria. Then we moved into marine proteobacteria. Not a big leap, but then we began looking at … metabolomics, and natural products in plants, fungi, and microorganisms. If you want to collaborate, let …
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Natural Prodcast Episode 14: Nigel Mouncey
… my undergraduate in microbiology and then PhD in microbial genetics in the UK. And came across to the US for a couple … of things. Full stretch all the way from a well into microtiter plate all the way up to supporting 200,000-liter … which, at least at the time, was called Inatreq . It’s a fungicide that is active against Sartoria which is a really …
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