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… Cas9 needs guide RNA to lead it to the correct sequence to snip — but not all guides are effective. To … approach: CRISPR-Cas9 relies on RNA with a short guiding sequence (20 bp) that directs the endonuclease where to cut, … , the scientists thus set out to identify which sgRNA sequences were reliable. In an elegant, quantitative screen, …

… CheckV can help researchers assess virus sequence fragments and data quality. The Science Through … and computational approaches, more and more virus sequences are being recovered and identified from … the quality and completeness of metagenome-assembled virus sequences vary widely. In a previous effort, an …

… first time, the sex chromosomes of shrub willow have been sequenced with sufficient resolution to analyze their … located at Lawrence Berkeley National Laboratory. The JGI sequenced the shrub willows through the  Community Science … Palindromes are large inverted repeats with highly similar sequences so that their sequences read the same (or nearly) …

… plant and algal functional genomics, inter-organismal interactions, understanding natural communities important …

… development, dozens of reference genomes and thousands of resequenced sorghum varieties, a resource for breeders and … high-quality reference genomes. By cataloguing a genome sequence for a line of sorghum, reference genomes have … Now, researchers have brought many reference genomes and sequences together at once, producing a pangenome resource …

… then used a series of random insertions of a foreign DNA sequence to generate a huge pool of mutants, each containing … died and others grew well; the survivors had their DNA sequenced at the JGI as part of a 2014 Community Science …

… Duke University, published their research related to how bacteria that colonize the roots of sphagnum work to … computer science, to reveal clues about how microbial and bacteria communities influence the carbon-sequestering …

… elements based upon their gene content and their genetic sequences. Roux was first author on a study featuring a new … to reliably match viruses with their archaea and bacteria hosts.  Jeremy Schmutz’s 2023 published work … that identified flagella in the terrestrial ancestors of marine-dwelling Chloroflexota, as well as a Nature …