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… have been elected to the User Executive Committee of the Joint Genome Institute, a Department of Energy user facility located at Lawrence Berkeley National Laboratory. Holly Bik of the University of Georgia, Greg Bonito of Michigan State …

… Metabolism   Although there are still a large number of secondary metabolites yet to be discovered and their … expressing a given BGC in various hosts, availability of sequenced genomes, and computing resources needed to predict BGCs from available genome sequences. The DOE Joint Genome Institute (JGI), a DOE …

…   Hosted by the DOE Joint Genome Institute, the University of Nevada, Las Vegas, and the Desert Research Institute, the … 2025 NeLLi Symposium delves into the most recent expansions of the Tree of Life and latest discoveries toward the … metabolic and functional capabilities. Take part in the "Sequences to Cultures" Jamboree!  Immediately following the …

… viruses outnumber the microbes by at least another order of magnitude. For years, scientists at the DOE Joint Genome Institute, a DOE Office of Science user facility located at Lawrence Berkeley … collection of UViGs by identifying contiguous viral sequences (“contigs”) from thousands of ecologically diverse …

… For the first time, a team analyzes the transcriptomes of a lichen fungus and alga to understand their partnership … is a superorganism: one being that is actually comprised of two (or more) participants. One is a fungus (usually … nitrocellulose filters in Petri dishes. The scientists also sequenced the fungus and photobiont’s genomes and compared …

… ( CRAGE ). CRAGE enables scientists to insert large pieces of DNA (up to 60 kb) in a single step, directly into the genome. “CRAGE is central to our ability to offer host-engineering for our users,” says JGI Director … domesticate some 60 strains, inserting into them a genetic sequence that acts as a “landing pad.” Mouncey adds, “Once …

… from single cells. The Science Studying the  genomes of microorganisms is incredibly useful for understanding the … Amplification to generate enough DNA to put on a sequencer. As previously mentioned, it’s a method that’s … assembly. So while researchers are confident all the DNA sequences came from one cell, including components like …

… just one research proposal. Guest speaker Michelle O’Malley of UC Santa Barbara talked about how her approved FICUS … Collaborations for User Science” (FICUS) program. Letters of Intent are due March 17, 2021. Q&A from the Webinar: … on the proposal call page. Feel free to  reach out to any of them with questions. Q:  Apart from instrumental support, …

… the microbial communities living in the mountaintop lakes of the Sierra Nevada mountains. These lakes are isolated, …

… school scientists. The Florida Everglades evokes images of fanboats skimming over swamps, while alligators peer through the waters and clouds of insects hover just above. Described as a “river of grass” that stretches some 580,000 square miles across … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science …

… Database provides details on river microbes in 90% of US continental watersheds. The Science In a recent Nature paper , researchers describe a dataset of microbial genomes sampled from rivers covering 90% of the … program at Pacific Northwest National Laboratory. The JGI sequenced over 1,000 metagenomes and established …

… to expression, scientists can now opt for various shades of grey. The ability to fine-tune the level of gene expression allowed researchers to identify variations of essential genes in metabolic networks that were missed … This work was funded by the Air Force Office of Scientific Research under Award No. …