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A Community Resource for Secondary Metabolite Researchers
… The Secondary Metabolism Collaboratory encourages user engagement. The … more than 13 million BGCs in the catalog at the time of publication, it is the largest repository of BGC sequence … repository of BGC sequences that come pre-annotated using multiple commonly used sequence analysis tools is a means of …
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How Much Do rRNA Gene Surveys Underestimate Extant Bacterial Diversity?
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Micro-Scale Applications Group
… The Micro-Scale Applications group explores the genetic makeup of natural microbial communities using a variety of … of single-cell genomes and directly link functional information with individual cells. Research Team    … The JGI uniquely offers the first quantitative Stable Isotope Probing (SIP) Metagenomics …
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Natural Prodcast Episode 2: The Primer, Part 2
… DAN: You’re listening to the US Department of Energy Joint … so secondary metabolism is throughout nature, except maybe for animals and humans, not as much. You know, we have this … live in the root nodules of plants. And these guys were sequenced, and you can see that different Frankia have …
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A New Actinobacterial Chapter in the Genomic Encyclopedia of Bacteria and Archaea
… Large-scale comparative analysis leads to identification of … gene clusters for novel secondary metabolites for multiple applications. The planet’s microbial diversity is … resource, but also yielding and supporting many high-impact publications ,” emphasized Markus Göker, who managed the …
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John Vogel
… Dr. Vogel joined JGI in 2014 to establish a plant functional genomics program. Prior to this, … he served as a Research Molecular Biologist at the USDA for 12 years where he was a driving force behind the … on developing plant functional genomic resources (e.g. sequenced mutant collections, transformation technology, …
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Strategic Integration of Multiple Bioinformatics Resources for System Level Analysis of Biological Networks
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Engagement Webinar: Utilizing long-read sequencing for metagenomics and DNA modification detection
… This webinar focused on how the JGI employs single-molecule, long-read DNA sequences to aid with genome assembly and transcriptome … Input & sequencing Q(uestion): How much DNA is needed for “regular” vs the ultra-low input library creation … The U.S. Department of Energy Joint Genome Institute, a DOE Office of …
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Gene Expression: From On-Off Switch to Dial
… Fine-tuning metabolic gene expression helps identify variants in yeast … approach to expression, scientists can now opt for various shades of grey. The ability to fine-tune the … to the results of the sugar-related tests, they pinpointed multiple genes that were previously missed in knock-out …
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Synthetic Biology Lab
… The Synthetic Biology lab is divided into a DNA synthesis production group and a … technologies to the broader community.  We focus our efforts on integrating database mining and sequence design with scaling the production of large, … For further details, please reach out to the Group Lead …
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Multiple genes recruited from hormone pathways partition maize diterpenoid defences
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First Monoploid Reference Sequence of Sugarcane
… Sorghum genome serves as a reference for the highly complex sugarcane genome . The … one from each parent. In contrast, many crops have multiple sets of chromosomes (they are “polyploid”) and their complex genomes are more difficult to sequence and assemble, in turn limiting the use of modern, …
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