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Natural Prodcast Episode 7: Ben Shen
… because they’re so reactive. BEN: …going back to the 1950s. But the structure of which was not known until the … different people have different numbers, but in general, an authoritative number for total number of natural products of … among the 70,000 microbial natural products total, about 500 drugs have been out of these natural products. So this …
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The Expanding Universe of Methane Metabolisms in Archaea
… available metagenome data provided by the other study co-authors, and reconstructed from these 10 … oldest metabolisms, with the first traces possibly at ~3.5 Gy (billion years),” Borrel and Gribaldo said in an email. … to Korarchaeota Drs. Luke McKay and William Inskeep are co-authors on the Borrel et al. study described above, and also …
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JGI Announces 2023 Community Science Program Awardees
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Designer DNA: JGI Helps Users Blaze New Biosynthetic Pathways
… publicly available for the research community,” says lead author Serina Robinson, a postdoctoral fellow at the ETH …
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Natural Prodcast Episode 10: A Primer on Genome Mining
… out where I got the chance to do genome mining on more than 50,000 genomes that we derived from meta-genome sequences. … Yu et al, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2004, 1253–1262, 70:3 ALISON TAKEMURA: And so did you succeed in … in this kind of a vein. We sequenced in the end about 150,000 genomes, just to look for a very specific class of …
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A Collaboration to Improve Plant Genome Annotations Across Species
Gene Atlas in  Nucleic Acids Research . The project spans 15 years and involves more than 17 research groups. The team … Manager Sarah Sharman recently interviewed study first author Avinash Sreedasyam, a HudsonAlpha senior scientist, … targets for plant improvement. Surprisingly, about 16 to 56 percent of plant genes are poorly characterized, meaning …
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JGI Hosts GPU Hackathon in May
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JGI@25: The Human Genome Project, or the JGI’s Origin Story
In honor of the JGI's 25th anniversary in 2022, we have revisited a number of … National Laboratory researchers were studying Chromosome 5, which contains about 6% of the human genome . They … human genome, an arms race was being waged. In this JGI@25 video, Susan Lucas, former JGI Production Department Head …
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Honey Bee Gut Microbiota Divvy Up Dinner
… these bacterial groups. But why the strain variability? The authors think the reason may be that … enzymes themselves. One other finding that interested the authors was that an evolutionary analysis of  … often lack the ability to break down hemicellulose. The authors think this might have to do with the differences in …
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JGI Scientists Pen Genome Watch Articles
… a model eukaryote. The wide array of topics comes from the authors’ interests, says Woyke. Their themes just need to … should be hot off the press. She tells prospective authors, “’Once you find a paper that you really like or are … about, take that topic and run with it — write about it.” Authors then float their ideas by Du Toit, sending her a …
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David Goodstein
… structural mutation in the laboratory. The Plant Cell 35 (2), 644-672 A Sreedasyam et al., 2023. JGI Plant Gene … across the plant kingdom. Nucleic acids research 51 (16), 8383-8401. JT Lovell et al., 2022. GENESPACE tracks … number variation across multiple genomes.  eLife 11, e78526. Li et al., 2021.  Plant Pan-Genomics Comes of Age . …
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JGI@25: Following Fungi that Pry Apart Plant Polymers
… 2022 marks the JGI’s 25th anniversary. Over the last year, we’ve been revisiting a …
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