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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… team  announced in  Nature Microbiology an important addition to the synthetic biologist’s toolkit: a technique for  c … system that allows scientists to conduct genome-wide screens and explore biosynthetic pathway. Thus far, the JGI has … domesticate some 60 strains, inserting into them a genetic sequence that acts as a “landing pad.” Mouncey adds, “Once …
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An Earth Month Look at Sustainability Efforts at the JGI
… Sustainable Berkeley Lab maintains a  calendar of Earth Month events throughout April. This year, a new group at the … Plant Sale. All year, the JGI helps support finding solutions to clean energy and environmental challenges. And many … to grow plants that are sustainable in many environmental sense, this is a very good club to join.” Interested in …
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Promoting the Power of Viral Metagenomics
… early 2020, people all over the world have been forced to confront the awesome power that viruses have to affect nearly … hydrothermal vents – and computationally identifying which sequences represent viruses that were present in the sample. … of Science User Facility  located at Lawrence Berkeley National Laboratory, is committed to advancing genomics in …
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Game On: High School Students Drive Everglades Metagenomics Study
… a member of JGI’s Sample Management Group, attended a conference in Florida to discuss a JGI pilot project … the experience below. In the summer of 2018, Jonathan Benskin was preparing to teach a second year A-Level Advanced … samples to the JGI for sequencing.  While JGI processed, sequenced, and analyzed the soil samples, the JGI offered 7 …
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Bacteria and Fungi Divvy Up the Work in Forest Floor
… Bacterial enzymes play second fiddle to those from fungi when it comes to breaking … first needed to build a detailed database on the denizens in the soil. While large protein databases, like … So, to be able to identify proteins, the team compiled DNA sequences (metagenomes) and messenger RNA sequences …
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Researching and Solving Real-World Problems with the 2023 JGI-UC Merced Interns
… Program was brimming with excitement and determination as they came onsite. From data carpentry to science … Comparative Analysis of Metabolic Pathways in Fungal Pathogens Shayna Bennett and mentor Robert Bowers, Mobile Genetic … mentor Bryce Foster, Benchmarking Bioinformatics Tools for Sequence Similarity Searching Morgan Lavenstein Bendall and …
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Tracking the Origins of Methane-Producing Microbes
… Methane-producing archaea are estimated to produce 500 million tons of methane a year, which is over half the total global … the microbes into small pools of cells that were then sequenced separately. From these samples, 111 … of Science User Facility located at Lawrence Berkeley National Laboratory, is committed to advancing genomics in …
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Engagement Webinar: What Can You Do With An Approved CSP Functional Genomics Call Proposal?
… On July 8, JGI’s DNA Synthesis Science group held a  JGI Engagement: Accessing Functional Genomics Capabilities Webinar inviting researchers to … the researchers will receive a FedEx package with the sequenced, quality controlled population representing the … of Science User Facility  located at Lawrence Berkeley National Laboratory, is committed to advancing genomics in …
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Applying Viral Genomics Expertise to Understanding the Human Virome
… tools and data hub for NIH program. While the microbes in, on and around Earth outnumber the stars in the Milky Way, … JGI team, including Kyrpides, Camargo, and Roux, has an extensive track record of developing cutting-edge tools for … collection of UViGs by identifying contiguous viral sequences (“contigs”) from thousands of ecologically diverse …
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Olpidium, The Key to the Origin of Terrestrial Fungi
… Before 2006, Olpidium was one of the many obscure fungi of Chytridiomycota (the … of binning methods, we were able to recover Olpidium sequences from the “contaminated” genome data with strong … reconstruction . We were also able to sample extensively among the early diverging terrestrial fungi (i.e., …
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An Enzyme System to Help Catalyze Bioproduction of Plastic
… By characterizing the structure and function of a methylthio-alkane reductase system, researchers … gaseous organic sulfur compounds in the atmosphere.  Beyond bacteria, this enzymatic machinery has potential as an … isolate it. The JGI provided a range of constructs based on sequences for MAR enzymes from different organisms to …
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UC Merced Interns Reflect on Their JGI Summer Projects
… students from UC Merced worked closely with JGI scientists on research projects that contribute to the larger mission of the U.S. Department of Energy. Students also worked … Intern: Sidharth Babu (undergraduate) Mentor: Zhong Wang Click the image to watch the video …
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