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JGI Announces FY26 Large Scale Portfolio for Our Community Science Program
… [Pictured from left to right are: [Above] Sara Branco, Asdrubal Burgos, Posy Busby, Hao Chen, … the research consortium aims to generate over a terabase of sequence. “We are thrilled to support this year’s CSP …
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Viral Genomics Group
… Microbes drive critical ecosystem functions and affect global nutrient cycling, however they do so under … While an ever-increasing number of phage and virus genomes have been assembled and reported from … Multiomics approaches such as metagenomics and metatranscriptomics …
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Innovative Technology Improves Our Understanding of Bacterial Cell Signaling
… developed chemiluminescent biosensors shed light on how bacteria function and colonize diverse environments. The … Ec YcgR, within the Nano-lantern scaffold. They then mined sequence databases for homologous YcgR proteins and chose a … These 92 homologues were synthesized as codon optimized sequences and cloned into the Nano-lantern scaffold. Because …
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New and Improved: Eucalyptus Reference is Now Accessible
… An improved genome assembly to support targeted tree … using advanced technologies to reconstruct the complete sequences of individual chromosomes. The team describes the … hypothesizes the difference might not be due to repeated sequences, but rather the more accurate assembly of regions …
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Dealing with Drought: Uncovering Sorghum’s Secrets
… Over 40 percent of the cereal crop’s genes respond to drought stress. The Science … conventional food crops. For that reason, its genome was sequenced by the JGI in 2009 and it is considered to be … diseases are well known to be partially due to the DNA sequence that makes up an individual’s genome. The genes of …
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Doubling Down on Known Protein Families
… Using a novel computational approach, researchers confirm … the process hinges on referencing to existing genome sequences.  Some of these proteins are what the scientists … artificial intelligence to decode the language of protein sequences and obtain hints of their possible functions. Yet …
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A Collaboration to Improve Plant Genome Annotations Across Species
… To provide broad plant genomic capabilities, the DOE Joint Genome Institute works in … Schmutz is the Plant Program Lead at the JGI. Sarah:  Why is a resource like this important to the field of plant …
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Here, There and Everywhere: Large and Giant Viruses Abound Globally
… JGI-led team significantly expands the global diversity of large and … genomes of uncultivated giant viruses from environmental sequences across the globe, then using these sequences to make inferences about the biogeographic … The U.S. Department of Energy Joint Genome Institute, a DOE Office of …
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Ian Blaby
… Since 2019 Dr. Blaby heads the DNA synthesis platform at the Joint Genome Institute, where he … with a view to developing a deeper understanding of sequence-based gene function. … B.Sc. (HONS) – University of Wales, Cardiff, Genetics Ph.D. – University of Cambridge., …
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GenomeOcean Leverages AI to Decode Nature’s Secret Language
… Trained on environmental data, a new JGI tool more accurately … community able to not just analyze but also create DNA sequences mimicking an array of microbial life. By … is capable of discovering and modelling complex biological sequences such as biosynthetic gene cluster structures. …
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JGI@25: Tracking & Subduing the Plague of California’s Oak Woodlands
… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable … of millions of trees in California alone. With the genome sequence in hand, the UC team led the charge to develop … Publication: Tyler BM et al. Phytophthora genome sequences uncover evolutionary origins and mechanisms of …
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Uncovering Novel Genomes from Earth’s Microbiomes
… Large-scale comparative analysis leads to identification of … under laboratory conditions, their genomes can’t be sequenced using traditional approaches. Identifying and … of metagenome-assembled genomes (MAGs) directly from sequenced environmental samples without needing to cultivate …
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