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An Enzyme System to Help Catalyze Bioproduction of Plastic
… By characterizing the structure and function of a methylthio-alkane reductase system, researchers could … North, assistant professor of microbiology at Ohio State University and senior author of this work.  North led the … innovation ecosystem. “At JGI, we’ve done the synthesis, metagenome mining, all the way from sequencing to functional …
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Natural Prodcast Episode 18: A CSP Primer
… while, but Natural Prodcast is back again for another round of episodes. If you stick around for the next few months, … a mixture of, for example, metatranscriptome sequencing, metagenomics, single cell genomics. We even do the flow … for you, we sequenced thousands for you or thousands metagenomes. And I think also the quality that we provide. So …
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Doubling Down on Known Protein Families
… online Oct. 11, 2023 in  Nature highlights the vast array of functional diversity of microbes through a novel approach … (IMG/M) database, they successfully crafted the Novel Metagenome Protein Families (NMPF) Catalog.  “We can now … of functional diversity as well.”  Researchers from Harvard University, Indiana University. University of Crete …
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GenomeOcean Leverages AI to Decode Nature’s Secret Language
… genome discoveries. Unlocking the intricate details of life’s genetic blueprint has long been a significant … the genome as if it were a language, then we can take advantage of existing methodologies developed for natural … or even build their own.” Researchers from Northwestern University, Johns Hopkins University, the University of …
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Boosting Small Molecule Production in Super “Soup”
… still work in cell-free environments? (Spoiler: Yes.) Think of cells as tiny factories: within their walls they have … Nature Communications , researchers led by Hal Alper at The University of Texas at Austin and Michael Jewett of … than were noted inside the cell. “One of the huge advantages of the cell-free system is that the cells are no …
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The Case for Conservation
… genome . Now, high-quality reference genome sequences of the male and female plants, each representing a single set of chromosomes, are available. The genome assemblies … “Why bother keeping this?” For Stuart McDaniel’s lab at the University of Florida, an answer is in sight for a similar …
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Understanding Wildfire Recovery, Starting in Soil
… A metagenomic look at the soil microbes present a year after a … begins at the forest floor. Within the soil, a microbiome of bacteria, viruses and fungi process carbon and nitrogen, … This work brought together researchers from Colorado State University, the US Forest Service, New Mexico State …
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Enhancing microRNA167A expression in seed decreases the α‐linolenic acid content and increases seed size in Camelina sativa
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Boosting Small Molecule Production in Super “Soup”
… Yeast strains engineered for the biochemical conversion of glucose to value-added products are limited in chemical … Nature Communications , researchers led by Hal Alper at The University of Texas at Austin and Michael Jewett of … than were noted inside the cell. “One of the huge advantages of the cell-free system is that the cells are no …
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Learning to Look
… “Where’s Waldo?” readers need to look for a number of distinguishing features. Several characters may be … use to conduct a similar type of search in microbial and metagenomic databases. In this case, the machine “learned” to … in bacterial immunologist Joe Bondy-Denomy’s lab at the University of California, San Francisco. Both are co-authors …
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Tapping the treasure trove of atypical phages
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Evolution of a Fungal Gene Expression Regulator
… Describing the largest analysis to date of the modified DNA base 5mC variations in fungi. The … and fungi run the gamut from mutually beneficial to antagonistic. In fungi, 5mC is often found in transposable … Ecology & Evolution , a team led by Robert Schmitz at the University of Georgia and including JGI researchers …
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