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Mutant phenotypes for thousands of bacterial genes of unknown function
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CSP New Investigator Call
… initiatives new to the JGI. Projects must be independent of ongoing JGI proposals, and lead PIs cannot have been lead … of a novel approach or form the foundation for a large-scale CSP proposal submission. Sequence requests should not … data usage by the applicant/community, and track record of the applicant.  Learn about the general review process or …
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Boosting Small Molecule Production in Super “Soup”
… Yeast strains engineered for the biochemical conversion of glucose to value-added products are limited in chemical … environment, which would be transformative at industrial scales. “Cell-free systems have been really powerful at … grams per Liter-hour in a system optimized for developing small-scale prototypes. Additionally, the team also used a …
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Secrets of the Needles: What Microbes do on Conifer Leaves
… Novel study looks at microbiomes in aerial surfaces of plants and their roles in … the leaf surface to broader forest and ecosystem processes revealed through their diverse genomic capabilities. Summary … ) conducted by the U.S. Department of Energy Joint Genome Institute ( https://ror.org/04xm1d337 …
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DAP-seq Drives Robust Mapping of Gene Regulation
… Multi-species assays yield an unprecedented view of plant evolution and adaptation.    Understanding how … intricate network of regulatory “switches” in plants at a large scale was akin to trying to chart every electrical … to these challenges.  DOE’s Office of Science is the largest supporter of basic research in the physical sciences …
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Natural Prodcast
… about natural products and the science and scientists of secondary metabolism. Natural products, secondary … are incredibly important to medicine, the environment, and human health. As the JGI acts on its goals in — and builds … research, “Natural Prodcast” serves as an important line of communication to the scientific community. Host Dan …
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JGI@25
… Celebrating 25 years of genomics research 2022 marked the JGI’s 25th anniversary. We revisited a number of notable achievements that showcase our collaborations and … the JGI’s 25th anniversary, the JGI mural references dozens of iconic JGI contributions to advancing the frontiers of …
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A framework for human microbiome research
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Meanders as a scaling motif for understanding of floodplain soil microbiome and biogeochemical potential at the watershed scale
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Rearrangement of a Large Novel Pseudomonas aeruginosa Gene Island in Strains Isolated from a Patient Developing Ventilator-Associated Pneumonia
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A Community Resource for Secondary Metabolite Researchers
… more than 13 million BGCs in the catalog at the time of publication, it is the largest repository of BGC sequence data from over 1.3 … the most comprehensive BGC database available at 10X the scale of the closest comparable database, and has the … U.S. Department of Energy Joint Genome Institute (https:// …
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Mapping the Earth’s Hidden Fungal Kingdom
… the diversity of plants. To put this evolutionary timescale in perspective, the genus Aspergillus has been … despite their ubiquity and ancient origins, fungi remain largely mysterious. Only about 200,000 fungal species have … Earth's fungal kingdom. The manuscript reviews about 200 publications linking evolutionary history and innovations …
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