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Single mutation at a highly conserved region of chloramphenicol acetyltransferase enables isobutyl acetate production directly from cellulose by Clostridium thermocellum at elevated temperatures
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Three pairs of fungal Trametes strains isolated from distinct geographic origins show conserved genomic features and adaptive response to plant biomass
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Jane Grimwood Named HudsonAlpha Genomics Chair
… large-scale multi-institutional JGI projects and resulting publications that Grimwood contributed to include: A 2021 … sequence of the complex switchgrass genome , using samples from common gardens growing across the country. The national … As well as the seminal Human Genome Project DOE Chromosome publications: The DNA sequence and biology of human …
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Promoting the Power of Viral Metagenomics
… DNA or RNA contained in a sample that has been collected from any kind of environment you can think of – animal … hydrothermal vents – and computationally identifying which sequences represent viruses that were present in the sample. From these data it is possible to answer a wide variety of …
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A Natural Mechanism Can Turbocharge Viral Evolution
… and viral genomes, as well as genomes sampled all at once from the same environment, called metagenomes. Why? Simon … gauntlet of other cell defenses that could prevent viruses from successfully replicating, even if they managed to enter … resource (award DEB170007), and through a Challenge Grant from the California NanoSystems Institute at the University …
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Busting the Unbreakable Lignin
… as well as degradation products that accumulated as the fungus did its work.  The UC Santa Barbara team worked with …
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Igor Grigoriev
… led annotation and analysis of diverse eukaryotic genomes, from protists to plants. In 2009, he launched the JGI Fungal … origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.  Science.  2012;336: 1715-1719. … Selected Publications …
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Draft genome and description of Consotaella salsifontis gen. nov. sp. nov., a halophilic, free-living, nitrogen-fixing alphaproteobacterium isolated from an ancient terrestrial saline spring
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Genomic analysis of 94 SEMIA strains isolated from common bean nodules: species diversity and genes related to nodulation, nitrogen fixation, and tryptophan metabolism
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Micro-Scale Applications Group
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Tracing the Evolution of Shiitake Mushrooms
… Lentinula   The Science Shiitake mushrooms get their name from the same place they often source their nutrients — the … A  new analysis takes a  genomic look at Lentinula samples from around the world. By complete sequencing of 24 new … mushroom genomes, and assembling genomes from 60 existing sequences, this work expands the family tree for Lentinula. …
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User Programs
… and metabolomics. Proposals must request capabilities from both JGI and the Molecular Foundry.  Submission …
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