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Scaling Up Existing Skill Sets
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Hiroshi Otani
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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
… a DOE Office of Science User Facility, is supported by the Office of Science of the U.S. Department of Energy … Charles Gawad has been supported for this work by a Chan Zuckerberg Biohub Investigator Award, NIH …
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Honey Bee Gut Microbiota Divvy Up Dinner
… that pollen’s pectin and hemicellulose are degraded mainly by just two clades:  Gilliamella,  which mostly resides in … — are digested further along: first, the pectin, mainly by  Gilliamella ; then the hemicellulose, mainly by  Bifidobacterium.  The process is a division of labor by …
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Complete Genome of Oil-Rich Alga Reveals Ideal Platform for Bioengineering
… foundation for metabolic engineering in oleaginous algae. By creating a telomere-to-telomere nuclear genome assembly, … solves a major challenge in algal engineering by allowing for dramatically more precise gene-targeting. … organism's ability to switch between autotrophic and heterotrophic growth enables production strategies that optimize …
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Extracting the Secrets of Secondary Metabolites
… in 2019. Now, that power is poised to grow exponentially by combining it with CRISPR.  By employing CRAGE, researchers are no longer limited to … luminescens proves fatal to insects. It is carried by an infectious nematode and releases toxins into the … The work conducted by the US Department of Energy Joint Genome Institute, a DOE …
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Secrets of the Needles: What Microbes do on Conifer Leaves
… species and sites, reflecting ecological patterns shaped by both local conditions and the movement of microbes … forest canopies.  The Impact This work, enabled in part by the U.S. Department of Energy (DOE) Joint Genome … genomic capabilities. Summary In a project supported by the JGI Community Science Program, University of …
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Corymbia Genome Expands Terpene Synthesis Knowledge
… of the E. grandis reference genome, an international effort by a team that included researchers at the DOE Joint Genome … of any currently sequenced plant, a number closely followed by E. globulus . Occurring in clusters or duplicate arrays, … of terpene products in nature. As part of a proposal by the DOE’s Joint BioEnergy Institute (JBEI), the JGI …
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Taking Stock of the Known and Unknown Microbial Space
… of biodiversity, they used five universally conserved, protein-coding marker genes on nearly 2 million genomes, … of the available datasets. Efforts to recover MAGs by extracting data directly from environmental samples over …
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A New Actinobacterial Chapter in the Genomic Encyclopedia of Bacteria and Archaea
… to define the current shape of the microbial tree of life by filling in genomic information for thousands of … a very large collection of type-strain isolates, provided by the Leibniz Institute DSMZ – German Collection of … DSMZ isolates, for which quality DNA has been provided by the team. These strains have been characterized …
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From Berkeley to Binghamton: Tracking Strawberry Evolution
… genome duplication occurs within a single species. By contrast, “allopolyploids” arise when different ancestral … oilseed crop false flax – genomes that have been sequenced by the JGI – and the common strawberry, which is octoploid … so that, Session said, other scientists can “follow a step-by-step process to apply it to any genome of interest.” This …
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Learning to Look
… July 22, 2019, in  Nature Microbiology , a team led by scientists at the U.S. Department of Energy (DOE) Joint … sequence is most likely not an inovirus. But if these nearby genes are both short and novel, then that’s a very good … diversity among inoviruses with more than 3,400 different proteins, many linked to key functions such as virion …
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