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Streamlining Regulon Identification in Bacteria
… the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at … Nature Communications on June 17 , 2022, was conducted by JGI Director Nigel Mouncey and research scientist Hiroshi Otani. Both are members of the JGI’s Secondary Metabolite Science Program, which Mouncey …
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Model Fern Reveals Insight into DNA Thievery in Ferns
… the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at … ( Learn more about OGG in  this episode of to the JGI podcast Genome Insider . ) Summary A recent paper … of seed plants and ferns. The genome is available on the JGI’s plant portal, Phytozome . Researchers hope to have …
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Extracting the Secrets of Secondary Metabolites
… the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at … CRISPR to knock out or activate genes, researchers at the JGI were able to monitor loss- and gain-of-function. The … uncharacterized biosynthetic gene cluster. That work by JGI researchers was published April 2022 in Cell Chemical …
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2025 Progress Report
… JGI researchers demonstrate how their laboratory and data …
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A Community Resource for Secondary Metabolite Researchers
… The U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at … from isolate and metagenome data.   The SMC ( smc.jgi.doe.gov ) is designed with two main objectives. First … on solutions.  Compared with past efforts at the JGI, like IMG-ABC, and other academic efforts, SMC is …
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An Enzyme Family that Helped Shape Nitrogen Metabolism on Our Planet
… the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at … for computational analysis of the AT enzyme family, the JGI provided DNA synthesis capabilities to enable functional … testing of these enzymes. Yasuo Yoshikuni, head of the JGI’s DNA Synthesis Science program, underscored the value …
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Finding the Fermenters
… the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at … metabolism from the literature. They then used the JGI’s GOLD and IMG data portals to get information about the …
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Busting the Unbreakable Lignin
… Research Center. O’Malley is also affiliated with JBEI. The JGI data portals and pipelines helped identify potential genes responsible for lignin deconstruction. (The JGI also conducted RNA sequencing and alignment to the …
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An Automated Tool for Assessing Virus Data Quality
… uncultivated viruses. Following up on those guidelines, JGI researchers have now developed CheckV (pronounced … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at …
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Iron-rich Microbial Mats’ Main Players: Marsarchaeota
… into the evolution of life on Earth. For decades, longtime JGI collaborator Bill Inskeep of Montana State University … (gene expression), and direct microscopy. Through the JGI’s Community Science Program , the team used metagenome … team had previously identified and characterized, also with JGI’s help. Additionally, the Marsarchaeota comprise 20-50 …
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The Surprising Structure of a Shrub Willow Sex Chromosome
… the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley National Laboratory. The JGI sequenced the shrub willows through the  Community … This work was supported by the NSF Dimensions of Biodiversity Program (DEB-1542509 to S.D., DEB-1542486 to LBS, …
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Making a Lichen Together
… the US Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility. Grigoriev and his team at the JGI contributed to annotation of the genomes, available …
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