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Uncovering Novel Genomes from Earth’s Microbiomes
… analysis leads to identification of biosynthetic gene clusters for novel secondary metabolites for multiple … small fraction of Earth’s microbial diversity. Because most microbes cannot be cultivated under laboratory conditions, … A public repository of 52,515 microbial draft genomes generated from environmental samples around the world, …
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iPHoP: A Matchmaker for Phages and their Hosts
… to commandeer. For bacteriophage viruses, these hosts are microbes like bacteria, not humans. With metagenomic … in all kinds of ecosystems. However, matching these viral genetic sequences to their hosts is crucial to understanding … these microbes. A better understanding of virus-host interactions opens the possibility of using phages to …
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A New Actinobacterial Chapter in the Genomic Encyclopedia of Bacteria and Archaea
… analysis leads to identification of biosynthetic gene clusters for novel secondary metabolites for multiple … diversity. The article adds to the compendium generated as part of Genomic Encyclopedia of Bacteria and … organisms to respond to environmental stresses or mediate interactions with each other (sometimes antagonistic ones, …
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DAS Tool for Genome Reconstruction from Metagenomes
… to other methods. The Impact Understanding how individual microbes interact with each other in a community, and … and characterizing entire microbial genomes from sequences generated from environmental samples. The work aligns with … members and their genome-encoded metabolic capabilities and interactions. Supported by JGI’s ETOP, this new tool will …
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JGI Launches Latest Strategic Plan
… For the Joint Genome Institute, the end of 2018 was marked by a celebration of contributing over one … and ESnet, as well as externally to prospective partners to generate awareness of and clarity about the JGI’s strategic …
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Analyses of expressed sequence tags from the maize foliar pathogen Cercospora zeae-maydis identify novel genes expressed during vegetative, infectious, and reproductive growth
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Genomic analysis of 94 SEMIA strains isolated from common bean nodules: species diversity and genes related to nodulation, nitrogen fixation, and tryptophan metabolism
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The genome portal of the Department of Energy Joint Genome Institute: 2014 updates
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Hiroshi Otani
… 2016, Dr. Otani has been studying secondary metabolism in microbes, particularly actinomycetes. His research activity … particularly interested in understanding how, when and why microbes decide to produce which metabolites. …
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Engagement Webinar: Utilizing long-read sequencing for metagenomics and DNA modification detection
… deeply are metagenomes sequenced? A:  For the next call ( CSP New Investigator ), up to 4 long-reads (PacBio) … but we can already provide raw mapping files as well as gene- and contig-level coverage. Other related products Q:  … has found that it’s not necessary to polish with both, and generally it’s more efficient just to make a single library …
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Doubling Down on Known Protein Families
… Nature highlights the vast array of functional diversity of microbes through a novel approach to better understand … sequencing allows researchers to study the entire genetic makeup of these communities via whole genome … of the samples, without being able to distinguish which gene belongs to each individual microbial species within a …
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A Cost-Efficient Way to Convert Yeast into a Cell Factory for Hydroxyapatite
… to recover high value products from human waste. They   genetically modified yeast to efficiently convert elements … and it could be sold in the United States for $50-200, generating a potential profit of $1.4 million annually.  The … New Process Uses Microbes to Create Valuable Materials from Urine …
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