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… Micro-Scale Applications group explores the genetic makeup of natural microbial communities using a variety of cutting-edge approaches.  Our group also seeks out new approaches that utilize microfluidics/microdroplet technology in order to enhance the … The JGI uniquely offers the first quantitative Stable Isotope …

… well-integrated across JGI departments to ensure a robust offering of sequencing capabilities and products to our users. This includes scaling the technologies and enabling state-of-the-art sample processing and sequencing capabilities. … An assay used for profiling transcription factor binding sites across entire …

… the slightly murky waters in the tube look like a scoop of stormwater, complete with leaves, debris, and even … recalled of her first impression. “We realized they were unique because it looked like a single cell. The fact that … ecosystem in the Caribbean,” Volland said. “In terms of metabolism, it does chemosynthesis, which is a process …

… The JGI’s DNA Synthesis Program supports a wide range of projects, from single-gene synthesis to the synthesis of entire chromosomes, advancing the development of biofuels, biochemicals and other bioenergy solutions.  … project. These advancements contribute to the development of new biofuels and sustainable biochemicals. The DNA …

… characteristics — creating many different ways of processing nitrogen. To boost crops more efficiently in … at how this enzyme family evolved across 90 species. “One unique thing about this work was our focus on all the … many organisms function, they have a sense of why nitrogen metabolisms can be so varied.  As evolution has progressed, …

… expertise and infrastructure enable a broad community of scientists and engineers to leverage our data to develop new algorithms, models and tools in support of DOE mission priorities. Data discoverability and … the JGI will move to a new login service, requiring the use of an ORCID account with two-factor authentication enabled …

… Ancient  Chloroflexota s ditched their flagella and other traits when … flagella in an unexpected place: hot spring-dwelling bacteria from the phylum C hloroflexota . Research shows … conditions. The microorganisms found there utilize a unique array of chemicals not typically found in oceans or …

… In honor of the JGI's 25th anniversary in 2022, we have revisited a … first closed and finished genome derived from an uncultured bacterial single cell – a symbiont of the green … microbial populations in oxygen minimum zones identified SAR11 bacteria as initiators of nitrogen loss in these …

… with their target genes. The Science Regulons are a group of genes that can be turned on or off by the same regulatory protein. Researchers demonstrated … particularly sigma factors that initiate transcription in bacteria. Using this technology, which combines an in vitro …

… Guiding Principles All staff members of the US Department of Energy (DOE) Joint Genome Institute (JGI) commit to … In working toward a shared vision with members of the JGI advisory committees, we welcome and encourage …

… a method that allows researchers to quickly modify diverse bacterial genomes. In 2019, the JGI’s Yasuo Yoshikuni and … ( CRAGE ). CRAGE enables scientists to insert large pieces of DNA (up to 60 kb) in a single step, directly into the … microbial communities to take advantage of their joint metabolisms. Because, together, microbes can be used to …