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Metabolomics Technology Group
… Our lab is using mass spectrometry based metabolite profiling to provide direct biochemical …
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Synthetic Biology Lab
… have developed and continue to improve automated assembly pipelines bringing in new technologies, in particular … of throughput. We also develop methods for efficient QA/QC based on next-generation sequencing technologies including … interested in:  characterizing novel enzymatic activities using phylogenomic driven approaches, and understanding the …
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Natural Prodcast Episode 21: Elizabeth Parkinson
… exposure to working with Streptomyces, learning more about genome mining, as well as isolation and a little bit of … your website that-- speaking of hormones, that you're also using hormones as this chemical communication signal. BETSY … students, we obviously can't put any antibiotics or antifungals in there. So they get just a smattering. JACKIE: …
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Evolution of a Fungal Gene Expression Regulator
… in fungi. The Science Changing an A, C, T or G in a genome sequence can lead to changes in protein structures … on the largest analysis of 5mC distribution across the fungal tree of life to date, involving more than 500 species … of specific 5mC methyltransferase (MTase) variants. Using new sequencing technologies for producing both …
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Improved Gene Annotation of the Fungal Wheat Pathogen Zymoseptoria tritici Based on Combined Iso-Seq and RNA-Seq Evidence.
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Natural Prodcast Episode 2: The Primer, Part 2
… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the … those those guys that move around or swarm – they might be using secondary metabolites to produce chemicals that would … of weird growths on livestock due to you know, bacterial or fungal infections. Yeah, okay. So he identified these things …
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Frequently Asked Questions: Proposal Submission
… limits, and instructions.  Many of the submissions are done using web-based forms.   To view the proposal templates, go to the proposal submission page , login using your JGI account (create one here if you don’t already … proposals are subject to JGI policies on Data Release and Publication .   Except for applicants to the CSP New …
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Microbiome Data Science Team
… include exploration of the global diversity of alternative genetic codes (Science 2014), unearthing hundreds of thousands of new viral genomes and their predicted hosts (Nature 2016, Science … 2018, Molecular Cell 2019) and massive reconstruction of genomes from uncultivated microbes (Nature 2019). Other …
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Natural Prodcast Episode 15: Katherine Duncan
… was really before– or kind of around about when the first genome sequencing was done. But natural products– marine … Dan Udwary: Aw! Kate Duncan: What’s also a bit confusing is I also work on Antarctic actinomycetes, actually. … is a whole bunch of information that maybe never makes its publication. And these are little tips, you know, how to …
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How Filamentous Fungi Sense Food
… researchers at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … This first paper integrating multi-omics data from this JGI fungal ENCODE proposal was  recently published in the  … fungi. The work also suggests a new approach to gene annotation, which then can be explored in depth for multiple …
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Natural Prodcast Episode 1: The Primer, Part 1
… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the … where this happened have a tendency to be susceptible to a fungal infection of rye grain – a specific fungus, Claviceps … about terms and so I will probably end up interchangeably using the term secondary metabolite and specialized …
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Igor Grigoriev
… the pharmaceutical industry. He holds joint appointments as Fungal and Algal Program Head at the JGI, a Senior Scientist … of California, Berkeley. He contributed to the Human Genome Project and led annotation and analysis of diverse eukaryotic genomes, from … Igor Grigoriev is the Fungal & Algal Science Program Head at the JGI. Click to …
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