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CRAGE-CRISPR facilitates rapid activation of secondary metabolite biosynthetic gene clusters in bacteria
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Metagenome Program
… in their natural environments. This work encompasses bacteria, archaea, and micro-eukaryoes, along with their … drive innovations that could advance our understanding of Earth’s ecosystems. … The Metagenome Program focuses on the …
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Community Science Program
The Community Science Program (CSP) provides the scientific community at large with access … of disciplines. Three calls fall under the umbrella of our CSP: The Large Scale call is for expansive projects that …
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Approved Proposals
… previous fiscal years for our Community Science Program (CSP) as well as the Facilities Integrating Collaborations …
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JGI announces 2023 CSP Functional Genomics awardees
… genomic information into biological function. Through our CSP Functional Genomics call , we look for projects that …
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Uncovering Novel Genomes from Earth’s Microbiomes
… to identification of biosynthetic gene clusters for novel secondary metabolites for multiple applications.       Despite … samples around the world, expanding the known diversity of bacteria and archaea by 44%, is now available and  described …
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JGI-UC Merced Interns Share Their 2021 Experiences
During the summer of 2021, 13 interns from UC Merced spent eight weeks working … development enrichment activities. For some students in the 2021 cohort, this was their first internship experience, …
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JGI Earth Month: Healthy Streams, Nutritious Microbes?
In April 2020, we mark both the 50th celebration of Earth Day on April 22, and DNA Day on April 25. As both Earth and DNA are close to our JGI hearts, we’re … So, Ed is trying to understand how the molecules in tiny microbes can impact whole ecosystems. Part of the …
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Streamlining Regulon Identification in Bacteria
… particularly sigma factors that initiate transcription in bacteria. Using this technology, which combines an in vitro … scientist Hiroshi Otani. Both are members of the JGI’s Secondary Metabolite Science Program, which Mouncey leads. RIViT-seq …
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A New Actinobacterial Chapter in the Genomic Encyclopedia of Bacteria and Archaea
… to identification of biosynthetic gene clusters for novel secondary metabolites for multiple applications The planet’s microbial … 11, 2022, in Cell Genomics , the team focused on Actinobacteria ( Actinomycetota ), a group of bacteria with …
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2021 Progress Report
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The secondary metabolism collaboratory: a database and web discussion portal for secondary metabolite biosynthetic gene clusters
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