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… of JGI and ExaBiome Project team, supported by the DOE Exascale Computing Project. The award recognized the release of MetaHipMer, an end-to-end genome assembler that supports “an unprecedented assembly of … sequencing and computational analysis that enable systems-based scientific approaches to these challenges.  DOE’s …

… Analysis group. In this role he supervises the Genome Assembly, QA/QC, and User Support Analysis teams. Together, … other vertebrate genomes. When he joined the JGI, he worked as a project scientist and then as a research scientist on projects to develop functional …

… Do metabolic pathways from engineered yeasts still work in cell-free environments? (Spoiler: Yes.) Think of cells as tiny factories: within their walls they have both the machinery to make products such as proteins, and the mechanisms for maintenance to keep …

… Do metabolic pathways from engineered yeasts still work in cell-free environments? (Spoiler: Yes.) Yeast strains engineered for the biochemical conversion of … productivities greater than the source strains. (Blake Rasor) Think of cells as tiny factories: within their walls …

… have revisited a number of notable achievements that showcase our collaborations and capabilities to enable great … over 27,000 microbial genes. These genes were identified based on their potential to efficiently degrade … powerful that they can process tough cell walls.  “The JGI was really leading the development of these approaches that …

… impact of a large-scale heatwave event in the ocean known as “The Blob.” The event was recorded during a long-term study of microbial communities in the northeastern subarctic Pacific Ocean. The Impact The microbial … This work was performed under the auspices of the Scientific Committee …

… a novel phylum-level lineage of archaea with at least two major subgroups dubbed Marsarchaeota. The Impact … number of biotechnological applications. Molecular biology has benefited from heat-stable enzymes derived from thermophiles, stabilizing the polymerase chain reaction technology that enables researchers to …

… for growth yet essential for survival, may now be easier to characterize following a proof-of-concept study in … tool for accurately editing genomes, its effectiveness has historically been limited due to the lack of robust tools … available for carrying CRISPR into microorganisms. CRAGE (Chassis-independent Recombinase-Assisted Genome Engineering) …

… conifer needle microbiome. The phyllosphere, which is known as the aerial surface of plants, is a comparatively understudied area of forest ecosystems as past studies have mainly focused on root-associated … This research was supported by the National Science Foundation (NSF) under …

… and accurately identify mobile genetic elements like plasmids and viruses. The Science Mobile genetic elements … Two of the most common forms of MGEs are viruses and plasmids. They can be found in virtually all of Earth’s … that happen between tiny organisms (microbes) located in soils and water. MGEs like viruses and plasmids drive …

… unique array of chemicals not typically found in oceans or soils.  A recent study published in  The ISME Journal     focused on a class within  Chloroflexota called  Dehalococcoidia . Some  … User Facility at Lawrence Berkeley National Laboratory, has unveiled these motility tools in hot spring  …

… Metagenomic datasets could help map out microbial diversity hotspots Over the past few decades, advancements in sequencing technologies … publicly available genome sequence data generated over the past three decades, their study assesses what fraction of the … sequencing and computational analysis that enable systems-based scientific approaches to these challenges.  DOE’s …