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Hiroshi Otani
Since joining the DOE Joint Genome Institute in 2016, Dr. Otani has been studying secondary metabolism in microbes, … technologies and methodologies that facilitate discovery of new secondary metabolites. Prior to joining the JGI, he … Mol. Microbiol. 87, 1223-1236. PubMed … Education … Publications …
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Shattering Expectations: Novel Seed Dispersal Gene Found in Green Millet
Survey of Setaria's natural diversity reveals seed dispersal in … for the first time. For years, Elizabeth (Toby) Kellogg and other researchers at the Danforth Plant Science Center … was green millet (Setaria viridis), a small model grass with a short lifecycle that uses a carbon fixation process …
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Extracting the Secrets of Secondary Metabolites
… survival, may now be easier to characterize following a proof-of-concept study in which researchers paired CRISPR and CRAGE technologies. While CRISPR (Clustered Regularly … payloads directly into diverse microbes. Combining CRAGE with CRISPR provides researchers with a powerful addition to …
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Bacteria and Fungi Divvy Up the Work in Forest Floor
… plant fibers. The Science Walk in a temperate forest filled with Norway spruce trees, and microbial activity teems … analyzing the enzymes present in the complex organic matrix of the forest floor, a team of researchers have found that … able to identify proteins, the team compiled DNA sequences (metagenomes) and messenger RNA sequences (transcriptomes) …
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How Filamentous Fungi Sense Food
… . The Science A team led by researchers at the University of California, Berkeley used a multi-omics approach to reconstruct and model gene regulatory pathways used by the filamentous … a job site for a task that requires a flathead screwdriver with a full toolbox including Phillips and specialty …
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Fishing for Novel Cellulose Degraders
A “bait and hook” single-cell genomic approach to bioprospecting. The Science One of the most vital pieces of equipment for fly fishing is a boxful of lures. Designed with feathers or wires to mimic an insect or a particular …
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Bidirectional titration of yeast gene expression using a pooled CRISPR guide RNA approach
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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
With a new methodology, scientists are now getting more … from single cells. The Science Studying the  genomes of microorganisms is incredibly useful for understanding the … attempt to put them back into the original genomes. These metagenome-assembled genomes (MAGs) that came from shotgun …
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JGI@25: Fueling Investigation into Methane-Making Microbes
In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable … livestock — specifically, from the methane-making microbes within their rumen. There is another climate-minded reason …
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Dan Rokhsar
… the founding Associate Director for Computational Genomics, and led the computational efforts directed towards the sequencing, annotation, and analysis of three human chromosomes. After successful completion of … IBM Watson Research Center, Yorktown Heights, NY … Publications … 2018 Marthella Foskett Brown Chair, …
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High‐throughput identification of novel heat tolerance genes via genome‐wide pooled mutant screens in the model green alga Chlamydomonas reinhardtii
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John Vogel
… years where he was a driving force behind the development of numerous genomic resources that fostered the widespread … switchgrass transformation pipeline and, in collaboration with industrial partners, generated hundreds of transgenic … Visiting Fellowship Australia … Education … Selected Publications … Awards and Service …
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