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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
A group led by JGI scientists have made strides in improving and applying a method that allows researchers … Mouncey. Using CRAGE, JGI has established a portfolio of microbial hosts that users can select to be engineered. … aim to inform the engineering of stable, synthetic microbial communities to take advantage of their joint …
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Expanding Virophage Diversity
… are small viruses with double-stranded DNA genomes that co-infect eukaryotic cells along with giant viruses. Virophages … are small viruses with double-stranded DNA genomes that co-infect eukaryotic cells along with giant viruses. Almost all … available metagenomic datasets in JGI’s  Integrated Microbial Genomes & Microbiomes (IMG/M) data suite—which …
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Making a Lichen Together
The Science The humble lichen is a superorganism: one being that is actually comprised of two (or more) … hundreds of microalgae are able to partner to form lichens. Studying the symbiosis by investigating a lichen’s genomes … could help inform efforts at bioengineering symbiotic microbial consortia for bioenergy crops. And because lichens …
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From Berkeley to Binghamton: Tracking Strawberry Evolution
In the summer of 2015, Adam Session was a postdoc working at … These days, Session is starting his lab at Binghamton “studying polyploids and transposon evolution, expanding on … in more species, as well as modifying this method to study other types of problems surrounding differential …
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JGI Early Career Researchers Featured in mSystems Special Issue
In a special issue of mSystems , out May 14, 2019, JGI … sequence reads to link mobile elements such as plasmids to microbial host cells. In a separate article, research … and experimental approaches with the aim of eventually studying virus-host dynamics in nature. In the last few …
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A Community Resource for Secondary Metabolite Researchers
Collaboratory encourages user engagement. The Science In addition to the core set of "primary metabolites"—chemical compounds shared by most living creatures for energy, growth and reproduction—most … a secondary metabolites portal within the Integrated Microbial Genomes and Microbiomes (IMG/M) system known as …
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iPHoP: A Matchmaker for Phages and their Hosts
…   To understand virus-host dynamics, computation helps fill in what cultivation can’t. The Science At first, viruses are merely toolkits. To do anything, they must find a host, and not just any host will do. … opens the possibility of using phages to engineer microbial communities. One day, these phages could boost …
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Access to Rock Star Scientists
Through the JGI-UC Merced Genomics Internship, graduate students Candace Cole, Mo Kaze, Akshay … JGI Mentors : Ben Cole & Axel Visel, Genomics of Plant-Microbial Interactions “The summer internship has further …     Mo Kaze, UC Merced JGI Mentor : Susannah Tringe, Microbial Systems Group “Everyone here is very kind and …
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An Inside Look at How Plants and Mycorrhizal Fungi Cooperate
A new view into a symbiosis could offer benefits to address climate change: pulling atmospheric carbon into soil and boosting biofuel … sharing.  Recently, researchers have been able to study both sides of this interaction up close, using RNA …
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Dealing with Drought: Uncovering Sorghum’s Secrets
… genes respond to drought stress. The Science Fields of drooping stalks and cracked earth are becoming common images in many regions due to more extreme … a limiting factor – before or after flowering. For the study, the team grew two sorghum varieties: one that …
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Accelerating Metagenomics Discoveries with Deep Learning
Berkeley National Laboratory (Berkeley Lab) and other institutions shared their works-in-progress with 86 participants in an online workshop to … Lab’s Biological Systems and Engineering), to assign microbial taxa (Andrew Tritt of CRD and, independently, Ying …
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Fungal Friends or Foes in Plant Roots
Uncovering associations between plant roots and fungi that can help … analysis identified fungal gene families that help determine if these fungi act as friends or foes. The Impact Microbial communities comprised of fungi and bacteria can …
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