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Mining Metagenomes for Cas Proteins
… Cas14 proteins discovered from JGI’s IMG/M database and … Institute.  The Science Researchers report the discovery of miniature Clustered Regularly Interspaced Short … mining the datasets in the Integrated Microbial Genomes and Microbiomes (IMG/M) suite of tools managed by the U.S. …
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An Addiction Crucial to a Fungus’ Reproduction
… A fungus relies on bacteria to regulate key components of … this mutualistic interaction has on these potential large-scale biodiesel producing fungi. Summary In heritable … the National Science Foundation and the National Institutes of Health. The work conducted by the U.S. Department of …
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Boosting Small Molecule Production in Super “Soup”
… Do metabolic pathways from engineered yeasts still work in … Yeast strains engineered for the biochemical conversion of glucose to value-added products are limited in chemical … environment, which would be transformative at industrial scales. “Cell-free systems have been really powerful at …
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Building Sphagnum Genomic Resources
… Sphagnome data would enable researchers’ insights on their … Science Program (CSP), researchers are developing a number of resources to build up Sphagnum as a plant model system … estimate that they hold about 25 percent of the world’s soil carbon. In high latitudes, sphagnum can also act as a …
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Igor Grigoriev
… Grigoriev joined the JGI in 2003, following his postdoctoral training at UC Berkeley and work in the pharmaceutical … at Lawrence Berkeley National Laboratory, and an Adjunct Professor of Plant and Microbial Biology at University of … genomes in the JGI MycoCosm portal. In 2018, he launched scale-up of algal geomics and PhycoCosm portal. Dr. …
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Hiroshi Otani
… Since joining the DOE Joint Genome Institute in 2016, Dr. Otani has been studying secondary metabolism in microbes, … technologies and methodologies that facilitate discovery of new secondary metabolites. Prior to joining the JGI, he … BS, Engineering, Tokyo Institute of Technology Master's, Biotechnology, University of Tokyo …
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JGI@25: Building a Better Bean
… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable … to their economies. It also plays an important role in soil health through nitrogen-fixation and holds clues for … P. vulgaris on Phytozome … Plant Datasets …
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A Pinch of Salt Activates Silent Gene Clusters in Streptomyces
… This single environmental trigger highlights efficiency for users requiring … to examine microbial chemical production. The Science Soil bacteria in the genus Streptomyces are nature's … chemical factories. They hold genetic blueprints for dozens of complex compounds, but stay largely dormant under …
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Enlarging Windows into Understanding Gene Functions
… JGI innovates protocol revealing how genetic variations in sequences affect traits. In a text file, the rows of letters A, T, C and G appearing over and over in a … capability; no one else can do it in the world at this scale.” A bottleneck in the DAP-seq protocol, however, is …
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2021 JGI Proposal Call Brings New Investigators into Community Science Program
… Accepted proposals emphasize JGI interests in algae and secondary metabolites. A total of 27 proposals have been  approved through the annual  … while also highlighting collaborative research of a scale exceeding a single lab’s capacity. Additionally, the … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science …
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How to Target a Microbial Needle within a Community Haystack
… A workflow for capturing the genetic make-up of specific … be sequenced. Their protocol,  detailed in the journal  Microbiome , combines multiple techniques and was … The work conducted by the U.S. Department of Energy Joint Genome Institute, a DOE Office of Science …
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Interdisciplinary delegation from the University of Duisburg-Essen explores collaborative opportunities with Lawrence Berkeley National Laboratory
… A two-day kick-off meeting held at Lawrence Berkeley … National Laboratory (Berkeley Lab) marked the visit of an esteemed interdisciplinary delegation from the … are excited to continue our fruitful collaboration in the microbiome space that has resulted in many impactful papers …
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