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… Proposals aim to sequence and annotate genomes from Antarctica to Africa to global … proposals have been accepted from 70 full submissions based on 92 letters of intent. Additionally, 40 percent of … sequencing and computational analysis that enable systems-based scientific approaches to these challenges.  DOE’s …

… After studying the mechanism of action of antifungal natural products … Genome Institute in 2004. The main object of her research was the symbiont community of a gutless oligochaete for which … Tanja Woyke is the Microbial Science Program Head as well as our Deputy of User Programs. Click to learn more …

… Researchers at the JGI develop a tool to quickly and accurately identify mobile genetic elements like plasmids and viruses. The Science Mobile genetic elements … called geNomad identifies and classifies MGEs based upon their gene content and their genetic sequences. …

… Dr. Yasuo Yoshikuni has been head of the DNA Synthesis Science Program since 2015. The mission of this program is to harness the power of DNA synthesis, strain engineering, and biosystems design for DOE-mission-relevant discovery and … Yasuo Yoshikuni is the DNA Synthesis Science Program Head at …

… A team has optimized a crucial part of CRISPR-Cas9 technology to … is a powerful, high-throughput gene-editing tool that can help scientists engineer organisms for bioenergy … These insights into  Y. lipolytica biology and lipid metabolism furthers the U.S. Department of Energy’s goal of …

… revealing how genetic variations in sequences affect traits. In a text file, the rows of letters A, T, C and G appearing over and over in a dizzying array of … factors that control how genes are turned on is known as DNA affinity purification sequencing or DAP-seq. The …

… The BioSANS instrument is at the Center for Structural Molecular Biology (CSMB) at Oak Ridge National Laboratory.   On March 2, 2021, the Environmental Molecular Sciences Laboratory hosted a webinar to showcase how researchers can gain access to the Biological …

… For the first time, a team has comprehensively described host-virus dynamics in a … mat. The Science In microbial mats, communities of microorganisms live among viruses that infect them. But what trends … metabolic rate of microbial communities. Because microbial metabolism affects the biogeochemical cycling of carbon, …

… National Laboratory (Berkeley Lab) marked the visit of an esteemed interdisciplinary delegation from the University … on the visit, JGI Director Nigel Mouncey expressed enthusiasm about the potential of this collaboration stating, “We … treatment as well as microbial ecology with a focus on metabolism and ecosystem health. To facilitate in-depth …

… but stay largely dormant under standard conditions. As described in a recent issue of mSystems , scientists … how a single stress signal rewires a bacterium's entire metabolism for chemical production, the study provides a … hold the potential to accelerate development of bio-based manufacturing processes for producing industrial …

… The JGI was honored to host some of the brightest minds in genetics as part of our  2022 Annual Meeting . The meeting was a hybrid event, with guests … they, what are they doing, and what traits are expressed based on their movement? Through the recombination process, …

… probing helps ID novel interactions between bacteria and fungi The Science Researchers have successfully automated aspects of a commonly-used process for studying microbial … DNA is manually separated into a few different groups based on its density — DNA containing isotopes is “heavier” …