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… hitchhikers. These organisms are abundant and yet exceptionally small, with mini genomes to match. As a result, they … to survive. To fill in their nutrient gaps, they must latch onto a larger host — often, a fellow archaeal microbe. … hitchhikers coexist is key for understanding their impact on wider ecosystems, but these symbiotic interactions are …

… In honor of the JGI's 25th anniversary in 2022, we have … number of notable achievements that showcase our collaborations and capabilities to enable great science that will help solve energy and environmental challenges. In March 2008, the genome sequence of …

… researchers have identified a virus protein tied to carbon cycling.  The Science Through a collaborative effort, … of Science User Facility located at Lawrence Berkeley National Laboratory (Berkeley Lab). Using 5,000 images of crystalized samples cloned and synthesized by the JGI, scientists have begun the …

… Leveraging massive comparative genomics to decode millions of mystery genes and lay a future-ready foundation     Over the past billion years, fungi have spread … Earth's fungal kingdom. The manuscript reviews about 200 publications linking evolutionary history and innovations …

… biosynthetic gene clusters.  The Science Microbial secondary metabolites, those molecules not essential for growth … may now be easier to characterize following a proof-of-concept study in which researchers paired CRISPR and CRAGE … with CRISPR provides researchers with a powerful addition to their toolkit to study gene function. As a …

… Over 40 percent of the cereal crop’s genes respond to drought stress. The Science Fields of drooping stalks and cracked earth are becoming common images in many regions due to more extreme weather events such as heat waves, … D.C.-D., R.O., J.W.T., J.D., J.P.V., P.G.L., and E.P.); Gordon and Betty Moore Foundation Grant GBMF3834 and Alfred P. …

… Machine learning methods were applied on sequenced fungal genomes to classify gene families. The Science As a proof of concept, researchers developed an algorithm that “taught” a … food crops and feedstocks for biomass and biofuel production. Learning about the ecology and evolution of  …

…   To understand virus-host dynamics, computation helps fill in what cultivation can’t. The Science At first, viruses are merely toolkits. … to understanding what these viruses can do. Building on existing virus-host prediction approaches, researchers … of Energy, Office of Science, Biological and Environmental Research, Early Career Research Program awarded …

… Fine-tuning metabolic gene expression helps identify variants in yeast genes. The Science … a more nuanced library approach to tuning gene expression in metabolic pathways. Compared to the traditional way, which leverages an all-or-nothing approach to … No. FA9550-14-1-0089, the Camille and Henry Dreyfus Foundation, and the JGI Synthesis Program under FP00005685. In …

… analysis to date of the modified DNA base 5mC variations in fungi. The Science Changing an A, C, T or G in a … can lead to changes in protein structures and functions, but the DNA bases themselves can also be modified. The best-known example of a modified DNA base is a methylation of the base cytosine at the 5th position on its carbon …

… Tracking evolution of symbiotic lifestyles across multiple fungal lineages. … able to carry out a broader analysis than had ever been done before to look at how multiple forest fungi have independently evolved to establish symbiotic relationships with plants (mycorrhizae), and particularly how …

… strategic plan outlines how the JGI will advance the bioeconomy, leveraging partnerships to advance foundational science, creating opportunities for the global research … the DOE Office of Science user facility with broader national efforts to promote and stimulate a bioeconomy, where …