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Heterologous Expression and CRISPR/Cas9-Assisted Manipulation of the Hybrid Gene Cluster Specifying the Biosynthesis of Meroterpenoids and Phenazines
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Trent Northen
… to link genomes with environments to understand how webs of microbes cycle carbon and sustain biomes via the development … Genome Engineering Enables Rapid Activation of Biosynthetic Gene Clusters. Nat Microbiol. 4(12):2498-2510. doi: … 10.1038/s41564-019-0573-8 Diamond S. et al. Mediterranean grassland soil C-N compound turnover is depth stratified, …
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Gut Fungi: Unexpected Source of Novel Chemicals
… Swift — verified that the fungi expressed biosynthetic gene clusters, which are “building blocks” of natural … products. The team then confirmed that these expressed genes translated into expected proteins. That work was done … fungal natural products, O’Malley and her team plan to use genetic tools to boost production and isolate the compounds. …
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Soil virus offers insight into maintaining microorganisms
… soil health. Summary Soil viruses are a reservoir of genetic diversity and capable of transferring genes from one host microbe to another, which can have a significant impact on …
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JGI@25: A Single Cell, Myriad Microbial Discoveries
… green sharpshooter. In 2012, single cells isolated from the microbes found in the oil plume from Deepwater Horizon oil …
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The fungus that made itself at home
… to a new ecological habitat. The Science By comparing genetic information from similar organisms, researchers have … to thrive in manmade environments. As reported January 5, 2018 in The ISME Journal , a team led by University of Oslo … inside homes, and in an environment that offers limited interactions with wild relatives. …
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Toward Understanding Phage:Host Interactions in the Rumen; Complete Genome Sequences of Lytic Phages Infecting Rumen Bacteria
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RegPrecise web services interface: programmatic access to the transcriptional regulatory interactions in bacteria reconstructed by comparative genomics
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Interactions among triphenyltin degradation, phospholipid synthesis and membrane characteristics of Bacillus thuringiensis in the presence of d-malic acid
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HT-SIP: a semi-automated stable isotope probing pipeline identifies cross-kingdom interactions in the hyphosphere of arbuscular mycorrhizal fungi
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CRISPR-resolved virus-host interactions in a municipal landfill include non-specific viruses, hyper-targeted viral populations, and interviral conflicts
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Methanogenesis and Salt Tolerance Genes of a Novel Halophilic Methanosarcinaceae Metagenome-Assembled Genome from a Former Solar Saltern
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