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… annotation in fungal genomes. The Science In a proof-of-concept study, researchers demonstrated that a new … closest relative S. paradoxus at high temperatures (39°C/102°F). The Impact One of the challenges in understanding wild … The work conducted by the US Department of Energy Joint Genome Institute, a DOE Office of Science …

… characteristics — creating many different ways of processing nitrogen. To boost crops more efficiently in … enzymes in specialized metabolism, organisms tend to evolve multiple copies of enzymes, similar to including half a … plant, fungi and animal. This analysis led them to identify 2,938 putative AT  genes. Within the AT genes identified …

… one constant for the Joint Genome Institute. On July 1, 2020, that all changed. Ray’s vigilant stewardship as JGI’s … as a typical monthly JGI All-Hands Meeting, after a couple of perfunctory items, the agenda went off the rails – according to plan but unbeknownst to Ray and …

… technology has changed dramatically over the last  25-plus years since the JGI’s inception, making it possible … before. In 2006, the JGI produced 33 billion base pairs of sequence; by 2023, that number was almost 717 trillion. Last year, the JGI surpassed three Petabases of data sequenced — that’s three-quadrillion base pairs of …

… Kjiersten Fagnan began working with JGI in 2012 as a NERSC bioinformatics computing consultant, after … closely with staff to understand the data-intensive nature of JGI workloads. Dr. Fagnan was appointed CIO of the JGI in 2016, and in 2018 was hired to be the JGI’s …

… plants; at least once during their evolution, the genomes of flowering plants multiply. Over time, plants lose many genes after such … genomes to a diploid state while retaining multiple copies of some genes. This polyploidization process is ongoing and … related to clean energy generation and environmental characterization and cleanup. The JGI provides integrated …

… BS – University of Arkansas, Fayetteville, Chemical Engineering Ph. D. – … 2024 Berkeley Lab Recognition of Excellence Award 2016 R&D … T., Ruebel, O., Northen, T., & Bowen, B. (2015). Analysis of metabolomics datasets with high-performance computing and …

… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that showcase our collaborations and … with the HudsonAlpha Institute for Biotechnology.   Publications Grimwood, J., Gordon, L., Olsen, A. et al. The …

… begins at the forest floor. Within the soil, a microbiome of bacteria, viruses and fungi process carbon and nitrogen, … the microbes within the soil. To get a clearer picture of how burned ecosystems return to health, researchers have … burned soils had in common.  To complete this analysis, a multi-institutional team of researchers collected soil …

… A team has optimized a crucial part of CRISPR-Cas9 technology to enable improvements in microbial … level, how does  Y. lipolytica work? The project was a multi-institutional effort led by then-graduate student Cory … MB) and NSF  1706545 (IW). HA and JW were supported by the Office of Naval Research under grant  N00014-15-1-2785 . JW …

… Dr. Eloe-Fadrosh joined the JGI in 2014 to pursue her research interests in microbial ecology … Her current research focuses on leveraging thousands of metagenomic datasets from host-associated and … Program Lead position in 2017. She also leads the DOE’s multi-lab National Microbiome Data Collaborative (NMDC). …

… Leveraging massive comparative genomics to decode millions of mystery genes and lay a future-ready foundation     Over … Earth's fungal kingdom. The manuscript reviews about 200 publications linking evolutionary history and innovations … that, “In the next few years, with advances in genomics and multi-omics, phenotyping and AI we should better understand …