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Marine Microbe Contains Multitudes
… A deep dive into microbial genomics reveals one bacterial species is made of four ecologically distinct groups with different … to the blue-lit twilight zone, to the continuous pressure of the dark abyss, 4000 m (2.5 miles) deep. Scientists have … #3777 (to EFD). The work conducted by the US Department of Energy Joint Genome Institute, a DOE Office of Science …
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Streamlining Regulon Identification in Bacteria
… RIViT-seq technology could speed up associating transcription factors with their target genes. The Science Regulons are a group of genes that can be turned on or off by the same regulatory protein. Researchers demonstrated … This work was supported by the U.S. Department of Energy Office of Science under Contract No. …
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An Automated Tool for Assessing Virus Data Quality
… Through advances in sequencing technologies and computational approaches, more and more virus sequences are being … (metagenomes). However, the quality and completeness of metagenome-assembled virus sequences vary widely. In a … across both datasets, separating these from the vast majority of other sequences that were incomplete fragments. …
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DAS Tool for Genome Reconstruction from Metagenomes
… Program (ETOP) , researchers have developed and improved upon a tool that combines existing DNA sequence binning … been utilizing metagenomics as a way to study a collection of hard-to-culture microbes, but the efficacy of this approach would be greatly increased by having the …
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Corymbia Genome Expands Terpene Synthesis Knowledge
… Genome annotations of two C. citriodora subspecies broaden understanding of the terpene synthase gene family across eucalypt … Sequencing and assembly data carried out by EMBRAPA as part of the  Corymbia  genome project was supported by FAPDF grant “Nextree” 193.000.570/2009. For the portion of the work conducted by the Joint Genome Institute and …
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In Hot Spring Microbial Mat, Viruses Ride “Piggyback”
… a microbial mat. The Science In microbial mats, communities of microorganisms live among viruses that infect them. But what trends govern those … interactions? Do generalist viruses run rampant, capable of infecting different host species? Or, do they tend to …
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Gut Fungi: Unexpected Source of Novel Chemicals
… The Science Anaerobic fungi, which die in the presence of oxygen, dwell in herbivore guts and help them digest their last leafy meal. In their evolutionary history, these fungi branched off early from aerobic fungi, which can breathe oxygen — … from Santa Barbara Cottage Hospital and the University of California, Santa Barbara and a gift from the Gordon and …
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Innovative Technology Improves Our Understanding of Bacterial Cell Signaling
… Newly developed chemiluminescent biosensors shed light on how bacteria function and colonize diverse environments. … di-GMP (Guanine Monophosphate) is found in nearly all types of bacteria and interacts with cell signaling networks that … role in regulating microbial cellulose production and biofilm formation, which affects a number of environments, …
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Virus Discoveries that Keep Getting Bigger
… single-cell work — have quickly accelerated understanding of giant viruses. The Science In the last thirty years, in environments all over the world, scientists have discovered … genomes than many bacteria. Until recently, understanding of giant viruses came primarily from sampling an …
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Open Frameworks Training the Next Generation of Scientists
… Educational training technologies provide opportunities for students and professors alike The Science In  PLoS Pathogens , a team of faculty and researchers describe a workforce development … and developmental support from KBase (The Department of Energy Systems Biology Knowledgebase). Myco-Ed is …
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A Pinch of Salt Activates Silent Gene Clusters in Streptomyces
… This single environmental trigger highlights efficiency for users requiring … chemical factories. They hold genetic blueprints for dozens of complex compounds, but stay largely dormant under standard conditions. As described in a recent issue of mSystems , scientists found that adding salt to the …
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Mining Metagenomes for Cas Proteins
… Institute.  The Science Researchers report the discovery of miniature Clustered Regularly Interspaced Short … Integrated Microbial Genomes and Microbiomes (IMG/M) suite of tools managed by the U.S. Department of Energy (DOE) … to accurately edit genomes (that is, repair gene mutations, and either delete or add genes in a precise fashion) …
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