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… ( CRAGE ). CRAGE enables scientists to insert large pieces of DNA (up to 60 kb) in a single step, directly into the … Mouncey. Using CRAGE, JGI has established a portfolio of microbial hosts that users can select to be engineered. … aim to inform the engineering of stable, synthetic microbial communities to take advantage of their joint …

… in  Microbiome , researchers from the US Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science facility, have increased the number of … available metagenomic datasets in JGI’s  Integrated Microbial Genomes & Microbiomes (IMG/M) data suite—which …

Genomes from uncultivated bacteria offers clues to ancestral bacteria’s energy sources. More … own food and generate oxygen as a byproduct. The abundance of oxygen shaped the evolution of life on Earth, and led to … researchers from the Bigelow Laboratory for Ocean Sciences, Microbial Genome Program head Tanja Woyke of the U.S. …

In a special issue of mSystems , out May 14, 2019, JGI researchers are among the authors who offer perspectives on what the next five years of innovation … sequence reads to link mobile elements such as plasmids to microbial host cells. In a separate article, research …

… user engagement. The Science In addition to the core set of "primary metabolites"—chemical compounds shared by most … growth and reproduction—most organisms produce a set of "secondary metabolites," chemical compounds that often … a secondary metabolites portal within the Integrated Microbial Genomes and Microbiomes (IMG/M) system known as …

With metagenomic sequencing, researchers have found more of these viruses than ever before, in all kinds of ecosystems. However, matching these viral genetic … opens the possibility of using phages to engineer microbial communities. One day, these phages could boost …

JGI-led team significantly expands the global diversity of large and giant viruses. While the microbes in a single … noted study senior author  Tanja Woyke , who heads JGI’s  Microbial Program . The team mined more than 8,500 publicly … and the Georgia Institute of Technology focused on microbial communities from freshwater ecosystems, including, …

… their work delivered during the 5th anniversary celebration of the internship program. Candace Cole, UC Merced JGI Mentors : Ben Cole & Axel Visel, Genomics of Plant-Microbial Interactions “The summer internship has further …     Mo Kaze, UC Merced JGI Mentor : Susannah Tringe, Microbial Systems Group “Everyone here is very kind and …

In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that showcase our collaborations and … from environmental samples — to identify over 27,000 microbial genes. These genes were identified based on their …

Scientists find bee gut microbes have a division of labor when it comes to metabolizing complex … Honey bees are invaluable pollinators — cupids of the plant world facilitating the remixing of genes in the … But scientists have wondered exactly how the microbial community carries out its helpful metabolism: …

… insights from metagenomic data. In deep learning, a branch of machine learning, data is passed through algorithms … into multiple interconnected layers. The architecture of these algorithms, inspired by communication networks … Lab’s Biological Systems and Engineering), to assign microbial taxa (Andrew Tritt of CRD and, independently, Ying …

… host health. The Science Researchers compared the genomes of fungi that colonize Arabidopsis thaliana roots with … determine if these fungi act as friends or foes. The Impact Microbial communities comprised of fungi and bacteria can thrive in plant roots. They play …