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The Power of One, Amplified
… genomics can add significant value to the other commonly used culture-independent sequencing approaches including … the planet’s nutrient cycles and are potentially of use in fields ranging from agriculture to biotechnology and … A few years ago, a candidate bacterial lineage was identified from microbial and metagenome sequence data sets …
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Triggering Morel Fruiting
… (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility,  reported on just how morel fruiting is triggered when nutrients are … continued to seek other ways to make morels fruit under artificial environments, a technique to supply exogenous … of Energy Joint Genome Institute, a DOE Office of Science User Facility  located at Lawrence Berkeley National …
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Olpidium, The Key to the Origin of Terrestrial Fungi
… (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility, found that the fungus Olpidium is a link in the evolution and transition of … describes the effort that led to the work published in Scientific Reports . Before 2006, Olpidium was one of the many …
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Gut Fungi: Unexpected Source of Novel Chemicals
… off early from aerobic fungi, which can breathe oxygen — just like we do. Oxygen is a rich source of energy, and because anaerobic fungi can’t harness it, scientists long held … proposal. The next step for the team was to try to identify what natural products the fungi were making. So, Trent …
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How Maize Makes An Antibiotic Cocktail
… a family of compounds that protects it against infections — using surprisingly few enzymes. The Science Maize ( Zea mays … called zealexins. Even though scientists have identified at least 15 zealexins, they suspect there are even more to find. Zealexins are produced …
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The Expanding Universe of Methane Metabolisms in Archaea
… insights into an ancient metabolism. Methane is a greenhouse gas 20 times more potent than carbon dioxide. Billions … (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility, for publicly available metagenome data … and short-chain alkane oxidation metabolisms. They also identified a set of 38 marker genes that serve as a core set of …
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Nikos Kyrpides
… at Argonne National Laboratory. Dr. Kyrpides’ research focus on Microbiome Research with an emphasis on Microbiome … Nature . 622(7983):594-602. Camargo AP. et al. (2023) Identification of mobile genetic elements with geNomad. Nat … S, et al. (2021) Metagenomic compendium of 189,680 DNA viruses from the human gut microbiome. Nat Microbiol . …
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Learning to Look
… Machine learning approach significantly expands inovirus diversity. To answer the question, “Where’s Waldo?” … (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility, developed an algorithm that a computer could … databases. In this case, the machine “learned” to identify a certain type of bacterial viruses or phages called …
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Ian Blaby
… the Joint Genome Institute, where he leads three groups focused on HTP DNA design and assembly, strain engineering and … a group lead at Brookhaven National Laboratory where he focused on functional genomics of phototrophs. Through this and … systems. PloS one. 15: 11. 2020 Blaby & Cheng, Building a custom high-throughput platform at the Joint Genome Institute …
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Yasuo Yoshikuni
… Biology Pathway Engineering group. His research focus includes engineering of non-model yeasts for production … microbe-microbe and plant-microbe interactions in various environments to improve crop yield, and developing a … startup, Bio Architecture Lab, Inc. (BAL), where he used systems and synthetic biology to discover novel …
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DAS Tool for Genome Reconstruction from Metagenomes
… The work aligns with the ETOP mission of providing JGI users with the most current technology and expertise in order to address pressing energy and environmental scientific challenges. In Nature Microbiology , a team led by … and soil from the Angelo Coast Range Reserve in California. Using DAS Tool on data from soil samples, researchers were …
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A Pinch of Salt Activates Silent Gene Clusters in Streptomyces
… This single environmental trigger highlights efficiency for users requiring multiple omics methods to examine microbial … chemical production. The Science Soil bacteria in the genus Streptomyces are nature's chemical factories. They hold … can use to design more efficient microbial factories. Identifying specific genes, regulatory elements and metabolic …
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