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Natural Prodcast Episode 6: Marc Chevrette
… cases. MARC: Yeah, and in some cases of really extremely small genomes, like symbionts that can’t live without their … resistance, so we’re looking in soil that’s extremely diverse, and then it comes from all over the world. And … of the opinion that on the geological timescale, that most bacterial natural product systems evolved, you know, a …
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Boosting Small Molecule Production in Super “Soup”
… work in cell-free environments? (Spoiler: Yes.) Think of cells as tiny factories: within their walls they have both … senior authors. “But this has been done most commonly in bacterial-based systems, and so one of the things that I … grams per Liter-hour in a system optimized for developing small-scale prototypes. Additionally, the team also used a …
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Natural Prodcast Episode 12: Nadine Ziemert
… pathways, and that really helped me to get an idea how diverse the secondary metabolites are, even if primary … Usually, in a lot of cases, we still have to go through publications to get proteins, and their functions, and all … hard to make a full story out of that yet. So we have some small, little stories, all the time. We have compared three …
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Expanding Virophage Diversity
… Virophages are small viruses with double-stranded DNA genomes that co-infect eukaryotic cells along with giant viruses. Virophages are small viruses … of 328 “high quality” (based on completeness) diverse new virophage genomes containing all four core … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility …
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Institutional User Agreements
… starts with a User Agreement — before any work can begin, including the submission of samples for sequencing, or the … rights in technical data, project reporting to the DOE, and publication requirements. An official with authority is … the Contracts Officer will send required paperwork to your institution. (Samples of the JGI User Agreement , JGI User …
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Natural Prodcast Episode 14: Nigel Mouncey
… biosynthesis to produce chemicals that have really diverse applications.  DAN: So on many of your PowerPoint … like I said. And I’m part of that. It’s a few of us now, small little group. What’s your vision for us in our group?  … help the Society grow. And so I’ve been the chair of the publications committee for the last, what is it now, five …
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Natural Prodcast Episode 15: Katherine Duncan
… Hey, Alison Takemura: Hey, Dan. Dan Udwary: Today we’re going to talk to Kate Duncan. And Kate is– I should ask, you … around countries. And I was actually in Croatia on a small island off the coast in the Adriatic Sea, and I … is a whole bunch of information that maybe never makes its publication. And these are little tips, you know, how to …
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Natural Prodcast Episode 11: Marnix Medema
… Dan Udwary: You’re listening to the Department of Energy Joint Genome Institute’s … tiny precursor peptide, encoding genes that encode the very small precursor peptides that end up being … Integrated Microbial Genomics at JGI, a large data set of bacterial genomes. And so yeah, we use antiSMASH to identify …
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Data Ecosystem
… The JGI is leveraging its current partnerships to offer new capabilities and … different organizations is discoverable and accessible. Linking the resources of powerful institutions like the JGI, … for scientific exploration, granting access to diverse datasets that deepen our understanding of how …
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Giant Bacteria Found in Guadeloupe Mangroves Challenge Traditional Concepts
… delicately above the leaf debris are revealed to be single bacterial cells, visible to the naked eye. The unusual size is notable … clusters. He dubbed these organelles “pepins,” after the small seeds in fruits. DNA clusters were plentiful in the … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility …
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A Cost-Efficient Way to Convert Yeast into a Cell Factory for Hydroxyapatite
… Innovative technology from this biomanufacturing … performing activities similar to the specialized animal cells or osteoblasts that make HAp. JGI researchers … using several microscopy techniques to confirm that the cells were producing HAp granules.  The JGI team …
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JGI@25: A Single Cell, Myriad Microbial Discoveries
… In honor of the JGI's 25th anniversary in 2022, we have … quantities of DNA derived from individual environmental cells. The proof of principle study built off earlier … first closed and finished genome derived from an uncultured bacterial single cell – a symbiont of the green …
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