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… then you need to go back to your extract and try to purify the molecule that’s causing that test to be successful. … natural product molecules might actually get to market in a year. And that would be a good thing. That would be high. … has evolved over, you know, probably – possibly billions of years. And so it is pretty used to the way that the assembly …

… on using genome-resolved metagenomic approaches to identify and characterize genomic information from uncultivated … e01280-22. 10.1128/msystems.01280-22 Clum, A. et al. (2021)  DOE JGI metagenome workflow …

… white papers. Applicants may submit up to two proposals per year (but may be listed as co-PI on an unlimited number of …

… the content produced by microbes the result of millions of years of evolution. And if we could actually link terms to … evolution is acting very strongly. There is very strong purifying selection, and what matters is a final product. So it … conditions, unless it happens on the long term, millions of years. So interesting case. It could well be that some of …

… and resources.     Director's Perspective Over the last year, the U.S. Department of Energy Joint Genome Institute … who made use of our data. We completed 39,870 projects in FY24 We generated 871 Terabases of sequence We synthesized … with large-scale advanced genomic capabilities. This year we brought online the latest short-read technology, the …

… of genome mining, which is using DNA sequence to identify and interpret biosynthetic, secondary metabolism … that, I wanted to tell a quick story. Looking back, the year was probably 2010, 2011, I was a, uh- actually, I’ve … time. So they had actually sequenced the genome a number of years earlier as one of the first Streptomyces genomes that …

… with a widening circle of researchers. That’s why each year we look for novel research projects — aligned with DOE … and environmental disturbances. Proposals are accepted year-round for this annual call; the next deadline for …

… houses Vibrio fischeri, it’s one strain and there have been years and years and years about 35-ish years, I think, now, studying … if they’re not clustered then maybe we’re not really identifying them very well. For sure. But plants certainly make …