Search

… the pharmaceutical industry. He holds joint appointments as Fungal and Algal Program Head at the JGI, a Senior Scientist … from protists to plants. In 2009, he launched the JGI Fungal Genomics program which resulted in over 2500 fungal genomes in the JGI MycoCosm portal. In 2018, he launched scale-up of algal geomics and PhycoCosm …

… what we’re calling a Primer. We wanted to try and give a general audience some of the basics of natural products … knowledge of modern biology. We’re trying to keep this as general as possible, but scientists love technical jargon. … where this happened have a tendency to be susceptible to a fungal infection of rye grain – a specific fungus, Claviceps …

… such as fully annotated genome assemblies or differential gene expression results. For DNA synthesis projects, JGI ships physical materials like expression constructs or sgRNA libraries to the user. Most … is active for 3 years with the possibility for extension. Fungal genomes, for instance, can take up to a year or more …

… that produces those. So it’s not a hard and fast rule, but, generally, animals do not have secondary metabolism that we … – but this this white blob is a fungus called Penicillium . Now called Penicillium . And so this was a … of weird growths on livestock due to you know, bacterial or fungal infections. Yeah, okay. So he identified these things …

… massive comparative genomics to decode millions of mystery genes and lay a future-ready foundation     Over the past … fungi remain largely mysterious. Only about 200,000 fungal species have been named. Among those sequenced, … Department of Energy (DOE) Joint Genome Institute (JGI)’s Fungal and Algal Science Program and JGI users have been at …

… Fine-tuning metabolic gene expression helps identify variants in yeast genes. The Science Scientists have developed a more nuanced …

… notable research and scientific collaborations in 2018. The cover is an image of Mono Lake, a saline soda lake …

… America brought to the UK? ROGER:  Yeah, it’s difficult to generalize, of course, but I felt overall that the British … my perspective, JGI has a large database of biosynthetic gene clusters and biosynthetic gene cluster fragments, and all kinds of other crazy things. …

… previous fiscal years for our Community Science Program (CSP) as well as the Facilities Integrating Collaborations …

… bioprospecting vs biopiracy, early stage drug discovery in general, and a possible data-driven future for plant natural … without giving any benefit back to the owners of that genetic material? So this is also relevant to bacteria. If … could be used to treat these highly resistant bacterial and fungal pathogens. And we’ve actually just wrapped up a year, …

… Tracing gene regulatory networks in the model fungus  Neurospora … project, which is aimed at determining the activity, expression and regulation of protein-coding genes. This first paper integrating multi-omics data from this JGI fungal ENCODE proposal was  recently published in the  …

… where I was a graduate student. Aflatoxin, of course, is a fungal natural product which is a liver toxin when humans … , I think you’ll have heard how a lot of us who work in fungal natural products, especially in the old days, saw how … see as the overall “theme” of your research? I know you’ve generally worked in various marine organisms. Except during …