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… (2022) Giant virus biology and diversity in the era of genome-resolved metagenomics. Nature Reviews Microbiology …

All staff members of the US Department of Energy (DOE) Joint Genome Institute (JGI) commit to Lawrence Berkeley National … operations, and scientific relevance and quality. … The DNA Synthesis Science Advisory Committee is chartered to offer … and strategic objectives of the microbial and metagenome programs. The committee serves as the program's key …

… of Intent is required. For accepted proposals, sequencing, synthesis, metabolomics and analysis will be paid for by the …

… explain this?  DAN: Pharma is “medicine” and cognosy is “knowledge”. So it’s knowledge of where medicines come from, … almost never Actinomycetes. And so when we look at their genomes we don’t get the same kind of information that we … in the organism in its sequence that encode for that biosynthesis. But sometimes you have to know what those are in …

For accepted proposals, sequencing, synthesis, metabolomics and analysis will be paid for by the …

… analyses, such as metabolic modeling, that go well beyond genome annotation and analysis. The JGI and KBase seek to … data on scales ranging from single genes and individual genomes to metagenomes to systems-level modeling and … Research Scientific Computing Center … DOE System Biology Knowledgebase … National Microbiome Data Collaborative …

Metagenome-assembled archaeal genomes provide new insights into an ancient metabolism. … Nature Microbiology , they mined the Integrated Microbial Genomes & Microbiomes (IMG/M) database maintained by the …

… 2014), unearthing hundreds of thousands of new viral genomes and their predicted hosts (Nature 2016, Science … 2018, Molecular Cell 2019) and massive reconstruction of genomes from uncultivated microbes (Nature 2019). Other … (2021) CheckV assesses the quality and completeness of metagenome-assembled viral genomes. Nature Biotechnol . …

Biological and Environmental Research program, the Joint Genome Institute provides advanced genomic capabilities, … integrated high-throughput sequencing, DNA design and synthesis, metabolomics and computational analysis that … a home it shares with the staff of the DOE Systems Biology Knowledgebase (KBase) and the National Microbiome Data …

Virophages are small viruses with double-stranded DNA genomes that co-infect eukaryotic cells along with giant … Virophages are small viruses with double-stranded DNA genomes that co-infect eukaryotic cells along with giant viruses. Almost all known virophage genomes share only four genes in common: major and minor …

The mission of the Joint Genome Institute is to serve the scientific community as a … computing (HPC) and data analysis.  The DOE Systems Biology Knowledgebase ( KBase ) integrates systems biology data and … and readiness to begin work, checking such factors as genome size, polymorphism level, sample quality and …