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New and Improved: Eucalyptus Reference is Now Accessible
… genome for eucalyptus in the July edition of the journal G3 Genes | Genomes | Genetics , with significant advances … and 2014 diploid genome reference was visualized with GENESPACE, a computational tool for comparative genomics.   … the 2014 reference, though they have similar numbers of genes. The team hypothesizes the difference might not be due …
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Extracting the Secrets of Secondary Metabolites
… because it allows researchers to delete or activate certain genes and assess how these edits affect functionality.  … a point of entry. By using CRISPR to knock out or activate genes, researchers at the JGI were able to monitor loss- and … data shows peaks and valleys in secondary metabolites as genes are edited. With the help of CRAGE, the pairing proved …
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Engagement Webinar: Harnessing JGI’s Metabolomics Capabilities
… or biological samples (like cell media or lake water) without doing a metabolite extraction? Or are these samples … metabolomic data from a whole microbial community, without having cell counts or biovolume? A: We typically use …
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Soil virus offers insight into maintaining microorganisms
… reservoir of genetic diversity and capable of transferring genes from one host microbe to another, which can have a … scientists can shed light on hidden components, including genes called auxiliary metabolic genes (AMGs) that have nothing to do with a virus’ primary …
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Silver age of GOLD introduces new features
… a broad range of activities from proposal intake to publication. Information is also obtained and cross-checked …
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Climate Change Threatens Base of Polar Oceans’ Bountiful Food Webs
… tend to be dominated by prokaryotes (microorganisms without a defined nucleus). Colder waters nearer the poles, … to identify the microbes. And in order to determine what genes the algae were expressing, the team sequenced their …
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Axel Visel
… Computational Biology , Nucleic Acids Research . Over 80 publications in peer-reviewed journals including Nature, … Rubin EM (2011). Metagenomic discovery of biomass-degrading genes and genomes from cow rumen . Science 331, 463-7. Visel … Selected Publications …
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Genetic and Functional Diversity Help Explain Pathogenic, Weakly Pathogenic, and Commensal Lifestyles in the Genus Xanthomonas
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JGI@25: Studying Sorghum’s Survival Skills
… reference genome for Sorghum bicolor . Since then, 2,993 publications, 107 patent applications, and 53 patents have … team collect diverse lines of sorghum to understand what genes exist across the species. Earlier pan-genomes for … Brachypodium distachyon ( 2017 ), have identified many more genes than found in the single reference genome, including …
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JGI@25: Cow Rumen and the Early Days of Metagenomics
… environmental samples — to identify over 27,000 microbial genes. These genes were identified based on their potential to … into larger and coherent pieces called contigs — into genes and even into genomes — from these environmental …
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Giant Bacteria Found in Guadeloupe Mangroves Challenge Traditional Concepts
… size is notable because bacteria aren’t usually visible without the assistance of microscope. “It’s 5,000 times … As Volland noted, “The bacteria contain three times more genes than most bacteria and hundreds of thousands of genome …
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The More the Merrier: Making the Case for Plant Pan-genomes
… of flowering plants multiply. Over time, plants lose many genes after such events, returning their genomes to a diploid state while retaining multiple copies of some genes. This polyploidization process is ongoing and many … pan-genome. A pan-genome is the nonredundant set of genes found in a species, but in this case, the team …
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