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Viruses Reprogram Cells into Different Virocells
Microbial cells infected by viruses undergo metabolic reprogramming. The … from The Ohio State University and the University of Michigan studying how virus infections cause significant … 1, and 20% to 40% of the microbes are infected at any given time. Microbial viruses can thus have significant impacts on …
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JGI@25: Following Fungi that Pry Apart Plant Polymers
… 25th anniversary. Over the last year, we’ve been revisiting a number of notable achievements that showcase our collaborations and … breakdown, extending into biochemical production.    Over time, as these projects have delivered results, they have …
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Crysten Blaby-Haas
Blaby-Haas joined the JGI in 2022 as lead of the Biomolecular Materials Initiative, a partnership … in bacteria and leveraging molecular biology and reverse genetics to test those hypotheses. From 2011 – 2015, she … Google Scholar … Education … Awards and Service … Selected Publications …
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Extracting the Secrets of Secondary Metabolites
… for survival, may now be easier to characterize following a proof-of-concept study in which researchers paired CRISPR and … is a technique researchers can use to integrate large genetic payloads directly into diverse microbes. Combining …
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An Automated Tool for Assessing Virus Data Quality
… (metagenomes). However, the quality and completeness of metagenome-assembled virus sequences vary widely. In a … perform functional assessment, host prediction, and phylogenetic analysis. The development of CheckV helps … of the blind men who encounter an elephant for the first time. Based on the single body part each blind man touches – …
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Supercharging SIP in the Fungal Hyphosphere
High-throughput stable isotope probing helps ID novel interactions between bacteria and fungi … The Science Researchers have successfully automated aspects of a commonly-used process for studying microbial … than DNA lacking isotopes. This manual collection of DNA is time consuming, tedious and potentially error prone, which …
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2024 Progress Report
… for a sustainable bioeconomy. Mission  As a U.S. Department of Energy Office of Science user facility, we provide … processed 13,700 metabolomics samples With our users, 247 publications were published   … Our primary objective is to … increased capacities and faster sequencing, and at the same time help us manage costs. We have also scaled DNA-affinity …
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The Expanding Universe of Methane Metabolisms in Archaea
Metagenome-assembled archaeal genomes provide new insights into an ancient metabolism. Methane is a greenhouse gas 20 times more potent than carbon dioxide. Billions of years ago, methane-producing archaea likely played a key …
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Celebrating a Decade of Science through the JGI-UC Merced Genomics Internship Program
… 2023 marked a decade since the inception of the flagship internship program … Research Opportunity Center, echoed similar sentiments for the undergraduate interns. For him, it was a …
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Igor Grigoriev
… at Lawrence Berkeley National Laboratory, and an Adjunct Professor of Plant and Microbial Biology at University of … Russia PhD in Molecular Biology, Research Institute for Genetics and Selection of Industrial Organisms, Moscow, … … Fungal & Algal Science Program … Education … Selected Publications … Awards and Service …
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Gene Expression: From On-Off Switch to Dial
Fine-tuning metabolic gene expression helps identify variants … to expression, scientists can now opt for various shades of grey. The ability to fine-tune the level of gene expression allowed researchers to identify variations of essential genes in metabolic networks that …
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High Five: Celebrating the JGI-UC Merced Genomics Internship Program
… than 20 UC Merced students have contributed to the research of 13 JGI scientists since the program’s inception. In 2014, JGI’s Zhong Wang and … who mentored 2018 intern Akshay Paropkari, echoed the sentiment, saying, “I wish Akshay could stay at the JGI for …
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