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Mining Metagenomes for Cas Proteins
… The ability to accurately edit genomes (that is, repair gene mutations, and either delete or add genes in a precise fashion) has applications across many areas. In particular, gene editing is being used to develop drought, flooding, …
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Natural Prodcast Episode 8: Eric Schmidt
… see as the overall “theme” of your research? I know you’ve generally worked in various marine organisms. Except during … really need to know how they’re made. You need to bring the genes into the lab, and you need to manipulate them in the … products made by animals, which is highly unusual, as it’s generally considered that it’s the bacteria living in …
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Tracking the Origins of Methane-Producing Microbes
… methanogenic archaea use one of three pathways for methanogenesis: hydrogen-dependent and CO2-reducing, or … and, acetoclastic. All three pathways require the gene cluster for methane production known as Mcr. Until recently, the Mcr gene cluster was found only in the archaeal lineage …
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First Monoploid Reference Sequence of Sugarcane
… in these crops. For diploid species, sequencing programs generally focus on a genotype with two identical sets of … sequence using a targeted approach that focused on the gene rich part of the genome by harnessing information from … The reference sequence is useful for mapping the genes involved in sugar production and for identifying …
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Synthesis
… into functional assessments. This is done by synthesizing genes, pathways, and whole chromosomes for bioenergy, … DNA Synthesis platform enables users to validate hypotheses generated from mining genomic data by designing and …
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New and Improved: Eucalyptus Reference is Now Accessible
… genome for eucalyptus in the July edition of the journal G3 Genes | Genomes | Genetics , with significant advances compared to the 2014 … tools has been critical. The new improved genome assembly generated through the JGI’s Community Science Program will …
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JGI@25: The Little Alga That Could
… of both plant and animal cells, it shares nearly 7,000 genes with other organisms (a third of those shared by both … and flowering plants). Its genome also contains hundreds of genes uniquely associated with carbon dioxide capture and the generation of biomass, making Chlamydomonas (affectionately …
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Fishing for Novel Cellulose Degraders
… DNA synthesis and cloning, followed by protein in vitro expression and mass spectrometry-based enzyme activity …
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JGI@25 RECAP: 2022 Annual Meeting features historical perspectives on JGI’s 25 years
… on, from the myriad of omics analyses for understanding gene expression in plants and the environment, to the JGI’s … in 2006 when the JGI transitioned from human to microbial genetics. Drell held the role until he retired in 2018. …
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A Sorghum Pangenome Opens More Doors to Discovery
… sequence for a line of sorghum, reference genomes have generated insight into drought tolerance, biomass production … for this plant. In other lines around the world, much more genetic diversity exists.  Now, researchers have brought … build a resource that demonstrates DNA sequence diversity, gene repertoire, and the phenotypic diversity across this …
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GenomeOcean Leverages AI to Decode Nature’s Secret Language
… discoveries. Unlocking the intricate details of life’s genetic blueprint has long been a significant challenge in genomics. Enter GenomeOcean, a powerful generative model  now available to the global research … an array of microbial life. By leveraging massive user-generated datasets at the JGI and other publicly available …
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Defining a Pan-Genome for Antarctic Archaea
… shed light on the global biogeography in the haloarchaeal gene pool, a team led by University of New South Wales … Rauer Islands. Additionally, they compared metagenome data generated from samples collected at four Rauer lakes to … a haloarchaea “pan-genome.” Described as the total pool of genetic material comprised by all members of a species, the …
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