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Tanja Woyke
… After studying the mechanism of action of antifungal natural products and their derivatives during … at the DOE Joint Genome Institute in 2004. The main object of her research was the symbiont community of a gutless … Tanja Woyke is the Microbial Science Program Head as well as our Deputy of User Programs. Click to learn …
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Computationally Classifying Fungal Lifestyles
… genomes to classify gene families. The Science As a proof of concept, researchers developed an algorithm that … part through the 1000 Fungal Genomes Project, including 55 newly-sequenced species.  The Impact The class  … Studies in Mycology , 2020.) Using whole genome data from newly sequenced genomes, they also built a high-quality …
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Trent Northen
… to link genomes with environments to understand how webs of microbes cycle carbon and sustain biomes via the development and application of advanced mass spectrometry approaches and model laboratory ecosystems (EcoFABs). … Trent Northen is the Metabolomics Science Program Head at the JGI. Click to learn more about the program's …
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Overview of the Genomes OnLine Database (GOLD)
… TBK Reddy gives an overview of the JGI's Genomes OnLine Database and why curated …
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Understanding Wildfire Recovery, Starting in Soil
… begins at the forest floor. Within the soil, a microbiome of bacteria, viruses and fungi process carbon and nitrogen, … the microbes within the soil. To get a clearer picture of how burned ecosystems return to health, researchers have … from Colorado State University, the US Forest Service, New Mexico State University, the Environmental Molecular …
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The Power of One, Amplified
… A preview of how large-scale single cell genomics complements … through metagenomics. Such techniques take advantage of bioinformatics tools for  extracting snippets of microbial … another might exhibit few limitations to interactions and new connections, thus sharing more ideas, similar to the …
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Decoding Yellowstone’s Microbial Mats
… began oxygenating Earth over two billion years ago. A team of researchers set out to Yellowstone National Park to study … mats. Along the way, they’ve encountered surprises, adopted new technologies, and made a few discoveries about the …
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Nandita Nath
… Nandita is involved in developing new methods to improve genome recovery from single cells and …
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Better Genome Editing for Bioenergy
… A team has optimized a crucial part of CRISPR-Cas9 technology to enable improvements in … tool will make the right cut, researchers created a set of guide RNAs that were effective against 94 percent of the … and xylose — into fatty acids that could be used for renewable fuel. In fact, lipids can make up more than 90 …
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2022 Progress Report
… Pictured is a timelapse of the Integrative Genomics Building (IGB) seen above is … Area are also co-located in the IGB. Vision The vision of the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office …
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Plotting a Model for Virus-Host Warfare Deep Below Ground
… Science Altiarchaea are carbon-fixing microbes and targets of multiple viruses in Earth’s deep subsurface. They are abundant representatives of deep subsurface ecosystems. A team of researchers described how the viruses repeatedly … Sloan foundation (grant number G-2017-9955), the Ministry of Culture and Science of North Rhine-Westphalia …
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A Pinch of Salt Activates Silent Gene Clusters in Streptomyces
… chemical factories. They hold genetic blueprints for dozens of complex compounds, but stay largely dormant under standard conditions. As described in a recent issue of mSystems , scientists found that adding salt to the … promoter sequences within these gene clusters, offering new regulatory targets for engineering efforts. Importantly, …
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