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Olpidium, The Key to the Origin of Terrestrial Fungi
… (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility, found that the fungus Olpidium is a link in the evolution and transition of … every family of fungi. In the following guest piece, JGI user Ying Chang in the Spatafora lab describes the effort …
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Gut Fungi: Unexpected Source of Novel Chemicals
… off early from aerobic fungi, which can breathe oxygen — just like we do. Oxygen is a rich source of energy, and because anaerobic fungi can’t harness it, scientists long held … source of antibiotics. Indeed, these anaerobic fungi may be using these compounds for self-defense. But the compounds …
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How Maize Makes An Antibiotic Cocktail
… a family of compounds that protects it against infections — using surprisingly few enzymes. The Science Maize ( Zea mays … scientists have identified at least 15 zealexins, they suspect there are even more to find. Zealexins are produced … a dozen enzymes. But researchers have now revealed that just a handful of enzymes are needed to transform zealexins …
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The Expanding Universe of Methane Metabolisms in Archaea
… insights into an ancient metabolism. Methane is a greenhouse gas 20 times more potent than carbon dioxide. Billions … (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility, for publicly available metagenome data … and short-chain alkane-oxidizing archaea. They used IMG because the database already contains metagenome …
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Celebrating a Decade of Science through the JGI-UC Merced Genomics Internship Program
… the summer of 2014 has grown to a total of 75 with the inclusion of the 2023 cohort. Each of them has brought … have a number of initiatives across several different campuses with this being our largest and most successful one. It’s proven to be a really good model for us that we try and continually replicate.”  On the other …
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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… is central to our ability to offer host-engineering for our users,” says JGI Director Nigel Mouncey. Using CRAGE, JGI has established a portfolio of microbial hosts that users can select to be engineered. “Piloting access to this …
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Learning to Look
… Machine learning approach significantly expands inovirus diversity. To answer the question, “Where’s Waldo?” … (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility, developed an algorithm that a computer could use to conduct a similar type of search in microbial and …
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JGI@25 RECAP: 2022 Annual Meeting features historical perspectives on JGI’s 25 years
… all that it has contributed, and what they’re excited about in JGI’s future. Find recordings and recaps of these … to be junk DNA, so there was quite a bit of resistance to use resources to sequence it,” Patrinos said. After many … of a genomic arms race as they recognized the private industry’s interest in simultaneously sequencing the human …
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Yasuo Yoshikuni
… Biology Pathway Engineering group. His research focus includes engineering of non-model yeasts for production … microbe-microbe and plant-microbe interactions in various environments to improve crop yield, and developing a … startup, Bio Architecture Lab, Inc. (BAL), where he used systems and synthetic biology to discover novel …
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DAS Tool for Genome Reconstruction from Metagenomes
… The work aligns with the ETOP mission of providing JGI users with the most current technology and expertise in … and soil from the Angelo Coast Range Reserve in California. Using DAS Tool on data from soil samples, researchers were … genomes with >90% completeness. These results, noted JGI User Programs Deputy Susannah Tringe , suggest that …
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A Pinch of Salt Activates Silent Gene Clusters in Streptomyces
… This single environmental trigger highlights efficiency for users requiring multiple omics methods to examine microbial … chemical production. The Science Soil bacteria in the genus Streptomyces are nature's chemical factories. They hold … , scientists found that adding salt to the growth medium caused Streptomyces coelicolor to activate multiple chemical …
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The fungus that made itself at home
… the dry rot ( Serpula lacrymans ) is so destructive in houses. A study involving six brown rot fungi reveals the … towards breaking down plant mass for conversion to sustainable, alternative biofuels and bioproducts. This study lends insights on how the fungus has responded to manmade changes in its ecological …
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