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JGI@25: Tracking & Subduing the Plague of California’s Oak Woodlands
… In honor of the JGI's 25th anniversary in 2022, we have … number of notable achievements that showcase our collaborations and capabilities to enable great science that will help … crisis implemented by the UC team was the development of a protocol for injecting a solution that bolsters the immune …
Learn more
An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… A group led by JGI scientists have made strides in improving and applying a method that allows researchers … team  announced in  Nature Microbiology an important addition to the synthetic biologist’s toolkit: a technique for  c … One , engineering different gene deletions in four gammaproteobacterial species, and then removing the editing …
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Cataloging the Microbes that Manage the Health of River Systems
… Database provides details on river microbes in 90% of US continental watersheds. The Science In a recent … 1,000 metagenomes and established standardized sequencing protocols so that researchers could compare results across … (DOE) Office of Science, Office of Biological and Environmental Research (BER) grants DE-SC0023084, DE-SC0021350, …
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Team Science Reveals Important Protein in Poplar
… Knockout experiments showcase potential for engineering bioenergy crops The Science Scientists at Brookhaven National Laboratory (BNL) led a team that  identified a protein , PtrbHLH011, within poplar involved in plant growth, … of Energy, Office of Science, Office of Biological and Environmental Research, as part of the Quantitative Plant Science …
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Expanding Horizons with the 2025 JGI-UC Merced Internship Cohort
… Interns contributed to a number of projects, from refining lab protocols at the bench to applying artificial intelligence to aspects of research questions Another intern summer has closed at the U.S. Department …
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A Model System for Perennial Grasses
… Panicum hallii genomes offer insights to drought tolerance. The Science Researchers have … complete genomes from varieties that diverged over a million years ago. The hallii variety thrives in desert environments, while the filipes variety is less drought tolerant …
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2024 Progress Report
… The Integrative Genomics Building (IGB) seen above is home to … from the DOE Systems Biology Knowledgebase (KBase), the National Microbiome Data Collaborative (NMDC), and Berkeley Lab Biosciences Area are also co-located in the IGB. Vision  Lead genomic innovation for a sustainable bioeconomy. …
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For the Tiniest Archaea, A Genomic Switch of Friend or Foe
… Meta-omics datasets show that CRISPR-Cas systems determine mutualism or parasitism between some archaeal hosts and … hitchhikers. These organisms are abundant and yet exceptionally small, with mini genomes to match. As a result, they … This shows that archaea may use CRISPR systems to protect against other, parasitic archaea. However, when  Ca . …
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JGI@25: The Human Genome Project, or the JGI’s Origin Story
… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that showcase our collaborations and capabilities to enable great science that will help …
Learn more
An Addiction Crucial to a Fungus’ Reproduction
… A fungus relies on bacteria to regulate key components of its reproductive machinery The Science To better understand how beneficial … This research was supported by the National Science Foundation and the National Institutes of Health. The work conducted by the U.S. …
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An Enzyme Family that Helped Shape Nitrogen Metabolism on Our Planet
… Researchers looked across many organisms to see that aminotransferase enzymes have evolved mix-and-match … To boost crops more efficiently in the future, the evolutionary past may hold key insights. The way that plants … These enzymes are crucial for creating nucleic acids and proteins, as well as recycling nitrogen. Now, with insight …
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Viruses Reprogram Cells into Different Virocells
… Microbial cells infected by viruses undergo metabolic reprogramming. The … But if the duck gets infected by a virus so that it no longer looks or quacks like one, is it still a duck? For a … For this project, RNA sequencing was done by the JGI, and proteomics and metabolomics analysis and microscopy at EMSL. …
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