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Wrinkles in the rare biosphere: pyrosequencing errors can lead to artificial inflation of diversity estimates
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Exploring Possibilities: 2022 JGI-UC Merced Interns
… their JGI mentors, what challenges they overcame, and what new skill sets they look forward to taking back to school.  … And also specifically, it sparked my interest in bioformatics, so that’s what I’m gonna take with me to the … are a little bit stronger in computing, so I was kind of worried coming into the, the internship that maybe I …
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Enlarging Windows into Understanding Gene Functions
… in sequences affect traits. In a text file, the rows of letters A, T, C and G appearing over and over in a … factors have been repurposed during evolution to control new functions,” O’Malley said. “Combining the two approaches … understand known biological functions as well as discover new functions. To help drive JGI User science we have …
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Expanding Horizons with the 2025 JGI-UC Merced Internship Cohort
… Interns contributed to a number of projects, from refining lab protocols at the bench to … communication and technical writing while also making new connections with both researchers and other interns. At … project, Hour mentioned that she had gained knowledge in bioinformatics and machine learning. “Also,” she added, ”I’ve …
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Gene Expression: From On-Off Switch to Dial
… to expression, scientists can now opt for various shades of grey. The ability to fine-tune the level of gene … approach to fine-tune gene expression. They tested this new methodology in yeast ( Saccharomyces cerevisiae) to … they are historically well-studied, Alper’s team discovered new gene targets to more efficiently grow on these sugars. …
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DAS Tool for Genome Reconstruction from Metagenomes
… been utilizing metagenomics as a way to study a collection of hard-to-culture microbes, but the efficacy of this approach would be greatly increased by having the … and interactions. Supported by JGI’s ETOP, this new tool will now be available for JGI users interested in …
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Georg Rath
… Before joining the JGI, he has been working on the boundary of life science and computational science with notable stops at NERSC, IMBA (Institute of Molecular Biotechnology, Vienna) and the High Field MRI Centre in Vienna, where he first stumbled from software development into building productive infrastructure …
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Seasonal Succession Leads to Habitat-Dependent Differentiation in Ribosomal RNA:DNA Ratios among Freshwater Lake Bacteria
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How Filamentous Fungi Sense Food
… . The Science A team led by researchers at the University of California, Berkeley used a multi-omics approach to … who show up at a job site for a task that requires a flathead screwdriver with a full toolbox including Phillips and … metabolized in filamentous fungi. The work also suggests a new approach to gene annotation, which then can be explored …
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Building Sphagnum Genomic Resources
… Science Program (CSP), researchers are developing a number of resources to build up Sphagnum as a plant model system … and researchers estimate that they hold about 25 percent of the world’s soil carbon. In high latitudes, sphagnum can … up nearly 3 percent of the earth’s land surface. In the New Phytologist, researchers led by David Weston of Oak …
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Celebrating a Decade of Science through the JGI-UC Merced Genomics Internship Program
… 2023 marked a decade since the inception of the flagship internship program between the DOE Joint Genome Institute (JGI) and University of California (UC), Merced. What started with 2 interns in … group at Oak Ridge National Laboratory, he has started a new position as the Senior Manager, Machine Learning at …
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From Stress to Growth: The adaptive mechanisms of algae in changing Arctic waters
… ice in the Arctic has decreased by more than 30% in terms of quantity and thickness. Replacing older, thicker ice with … surface where algae grow. Armed with a better understanding of the alga’s stress resistance and ability to adapt to … the adaptive mechanisms of Arctic microalgae but also opens new avenues for utilizing these organisms in sustainable …
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