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DAP-seq Drives Robust Mapping of Gene Regulation
… deciphering the complex wiring behind a city’s power grid. Just as the flow of electricity controls when and where … determines when and where genes are activated to sustain life’s processes.  Traditionally, mapping this … from grasses to broccoli and trees like poplar, spanning about 150 million years of evolution,” said Leo Baumgart, …
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A New Actinobacterial Chapter in the Genomic Encyclopedia of Bacteria and Archaea
… analysis leads to identification of biosynthetic gene clusters for novel secondary metabolites for multiple … (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley National … information as well as of important descriptive metadata about each strain. “This has been a very fruitful …
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Draft Genome of Janthinobacterium sp. RA13 Isolated from Lake Washington Sediment
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A Pinch of Salt Activates Silent Gene Clusters in Streptomyces
… This single environmental trigger highlights efficiency for users requiring multiple omics methods to examine microbial … chemical production. The Science Soil bacteria in the genus Streptomyces are nature's chemical factories. They hold … , scientists found that adding salt to the growth medium caused Streptomyces coelicolor to activate multiple chemical …
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Evolution of a Fungal Gene Expression Regulator
… the genome. Many plant pathogens such as the fungi that cause poplar leaf rust, are rich in transposons, which may help the pathogens … (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility, and others like it, are uncovering the true … The work conducted by the US Department of Energy Joint Genome Institute, a DOE Office …
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2021 JGI Proposal Call Brings New Investigators into Community Science Program
… (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley National … proposals come from investigators who have not previously been a principal investigator (PI) on an approved JGI … University of East Anglia was also approved to learn more about the roles of diatoms in carbon fixation and in aquatic …
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Tracking the Origins of Methane-Producing Microbes
… the total global methane production. They are thought to use billions of tons of the carbon dioxide trapped in … on the global carbon cycle. All methanogenic archaea use one of three pathways for methanogenesis: … and, acetoclastic. All three pathways require the gene cluster for methane production known as Mcr. Until recently, …
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JGI-UC Merced Interns Share Their 2021 Experiences
… working virtually with JGI mentors to investigate rigorous research projects, hone science presentation skills, and … returned to re-engage with their mentors from the previous year and continue working on their research project! The … foster a diverse future workforce in science. To learn more about each intern’s experience during their internship, …
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Len Pennacchio
… Pennacchio joined the DOE Joint Genome Institute and has focused on applying state-of-the-art molecular methods to … at Stanford University where he uncovered the genetic cause of a rare form of human epilepsy and subsequently generated one of the first mouse models for this common neurological disorder. In 1999, …
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Mapping Heat Resistance in Yeasts
… species to grow better than its closest relative S. paradoxus at high temperatures (39°C/102°F). The Impact One of the … DOE Joint Genome Institute (JGI), a DOE Office of Science User Facility of Lawrence Berkeley National Laboratory, aim … a way to map associations between genotype and phenotype using a strategy called reciprocal hemizygosity analysis via …
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Steven Wilson
… and our institutional website.   Mr. Wilson brings a user-centered approach, an ability to work with others to … with the Informatics Department to develop software that pushed instrument run information directly into the database … rather than depending upon error prone, manual input by the users in a web browser interface. Mr. Wilson then served as …
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An Addiction Crucial to a Fungus’ Reproduction
… A fungus relies on bacteria to regulate key components of its … evolved from a parasitic interaction with their soil fungus host, Rhizopus microsporus . Researchers found that … and a part of the oil-producing Mucoromycotina group, about which little is known. The Cornell team cultivated and …
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