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… about the basics of genome mining, which is using DNA sequence to identify and interpret biosynthetic, secondary … home. Or actually not my room, it’s the room of my little baby daughter, who inherited this room from her sister. And it … biological perspective, like what was this bacterium, and why did your group want to study it? Marnix Medema: You mean …

… stories about natural products, so you can get a feel for why I think they’re so important, and we’ll start to explain … search away! If you like these primer episodes, let me know by emailing us to [email protected], or on twitter @JGI or … Secondary Metabolites Science Program here at JGI. It’s a new group formed under the director who has also got a long …

… of sequencing data for synthesis. This agreement, required by the DOE for all work performed in its User Facilities, is … execute a 2024 version .  The recent updates were approved by the DOE to address the DNA Synthesis program. When fully executed, the new User Agreement will replace the active version. For …

With a new methodology, scientists are now getting more complete … Amplification to generate enough DNA to put on a sequencer. As previously mentioned, it’s a method that’s … a DOE Office of Science User Facility, is supported by the Office of Science of the U.S. Department of Energy …

The Scientific Advisory Committee (SAC) is a board convened by the JGI Director to provide a scientific and technical … technical input on large-scale production sequencing, new sequencing technologies, and related informatics; … and Environmental Research (BER) program, set the final sequence allocation for this program. …

… then genomics happened. Dan: Yeah, I did my first genome sequence with you. Brad: That’s right,  Dan: JGI did it in … called Salinospora . This new genus was discovered by friends and colleagues at the Scripps Institution of … working with you, Dan, on this one, and we said, “Well, why don’t we have you know, the bioinformaticians go against …

… you bring a unique perspective too? And so I was fascinated by – we spend a lot of time as natural products chemists and … does some really exciting work there. And I thought, well, why don’t we try to go to Alaska and see what we can find … with any kind of gene cluster identification, doing it with sequence alone you have to have some kind of a template to …

… we don’t recognize, because the only way to find things is by comparison. We’ll talk about that when we talk about … DAN: Alright, so I think we’ve covered a little bit about why they’re important. But one of the things I did want to … live in the root nodules of plants. And these guys were sequenced, and you can see that different Frankia have …

… term you prefer. In this episode we’re going to finish up by talking about the modern, post-golden age history of … able to explore DNA sequencing and actually get to the DNA sequence – sequences for the genes that code for the … Something that’s you know …  ALISON: Central! DAN: That’s why they called it that! But for, maybe, people who are less …

… datasets, particularly for uncultivated microorganisms, by sequencing large populations of bacteria and archaea in … resequencing, RNA sequencing and epigenomics. Expansion of sequence space:  The JGI generates reference genomes from … of microbial communities based on their metagenome sequence, in the context of reference isolate genomes …

… in the analysis and publication of the claimed genome sequences. This opportunity, provided by the Department of Energy Joint Genome Institute, builds … Reach the next generation of genome scientists and recruit new talent for biosciences.  Adopt-a-Genome has:  11 CSU …

… synthesis, metabolomics and analysis will be paid for by the Department of Energy’s funding of the JGI. There is … of funds.   Proposal Call FICUS CSP Large Scale CSP New Investigator CSP Functional Genomics Status CLOSED … to biological function Details Proposals must be preceded by Letters of Intent and must use a variety of capabilities …