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… “We thought about reconstructing gene regulatory networks, understanding where transcription factors bind in the genome. A key aspect of the project is understanding what TFs and regulatory networks are conserved …

… characterizing the planet’s microbial diversity is key to understanding the roles of microorganisms in regulating … Biotechnology . Known as the GEM (Genomes from Earth’s Microbiomes) catalog, this work results from a collaboration … it was a nice example of “big-data” mining to gain a deeper understanding of the data and enhancing the value by making …

… activities using phylogenomic driven approaches, and understanding the design principles for successfully …

… they deserve. They are so exciting. I get frustrated. Like microbiomes  – you know how that’s a big deal now. You go to all these meetings on microbiomes they only talk about the bacteria. My god! 30% … to me exactly in that point. We have some really great microbiome folks at UW and they collect all this DNA from …

MARC: Well, I’m really biased and I like the bugs in the microbiome. So a lot of my work is as focused on insects As … for many millions, sometimes billions, of years. And understanding how those changes that evolution brokers are … from day to day, year to year, and over millennia. So understanding how genes are changing and how chemistry is …

… which includes screening methods, genome mining in cave microbiomes, and using engineered biosynthetic pathways and … very rich environments. And they look a lot like most soil microbiome systems. And it makes sense because they are … in everninomicin and analogs of that, you’re really understanding one specific biosynthetic pathway. I guess how …

… public datasets.  … The Integrated Microbial Genomes & Microbiomes system ( IMG/M ) supports the annotation, … and distribution of prokaryotic microbial genome and microbiome datasets. It includes JGI-sequenced and publicly …

Their data report, which provides the only known reference microbiome data sets for the Loxahatchee Refuge,  was published in the journal  Environmental Microbiome . “Before JGI was involved, I was not sure we … sent through JGI’s  Integrated Microbial Genomes & Microbiomes (IMG/M) system, reached  Emiley Eloe-Fadrosh , …

… the sponges or other things. And we know lots more about microbiomes and symbionts that live with other organisms, … of secondary metabolism in the environment, and, sort of, understanding – like we’ve talked about – how bacteria or … a lot of bacteria out there. We’re definitely outnumbered. Understanding all of that chemistry is pretty important to …

… analytical standards to accurately measure environmental microbiome activity levels.This functional assay lets us …

… a member of the Functional Annotation team within the JGI’s Microbiome Data Science group. “Turns out that despite all … global nutrient cycles. The information gained from understanding the interactions between microbes, hosts, and … cultivate new microbial species.” Targeted Explorations for Understanding the Microbial World Corresponding author …